Solitary pulmonary nodules are frequently seen during thoracic imaging examinations. The majority of solitary pulmonary nodules are caused by cancer or infections, notably granulomatous infections. Lesions emerging from a bronchus are a less common source of single pulmonary nodules on thoracic imaging tests; the majority of such lesions reflect airway malignancies, such as carcinoid tumours and small salivary gland tumours. Primary endobronchial neoplasms, both benign and malignant, frequently show as a lobulated, polypoid lesion linked with an airway, sometimes accompanied with postobstructive consequences such as pneumonia, atelectasis, or gas trapping, on imaging tests, particularly thoracic computed tomography. Malignant endobronchial lesions may also exhibit more aggressive characteristics, such as locally invasive behaviour, regional lymphadenopathy, or even metastasis. A variety of uncommon malignancies can develop in the lung parenchyma and bronchi. Pneumocytic adenomyoepithelioma is one such uncommon lesion that has only lately been characterised.

This tumour is similar to other small salivary gland neoplasms in that it has epithelial and myoepithelial characteristics, but it also has pneumocytic differentiation. Little is known about the clinical and imaging characteristics of this uncommon submucosal gland bronchial malignancy.