The goal of this study is to evaluate the most recent research on particular immunoglobulin (Ig)E antibodies for predicting clinical reactivity to meals. Patients with persistent hen’s egg and cow’s milk allergies have greater antigen-specific IgE levels than individuals who have outgrown these allergies at all ages. According to recent research on the natural histories of hen’s egg and cow’s milk allergies, baseline antigen-specific IgEs are the most important predictors of tolerance. Oral immunotherapy (OIT), a new therapeutic strategy for food allergy, necessitates the use of biomarkers to predict treatment results. According to several research, the initial antigen-specific IgE level may be a helpful biomarker for the prognosis of OIT. Component-resolved diagnostics (CRD) has recently been utilized to diagnose food allergies. According to recent research, Ara h 2, omega-5 gliadin, and ovomucoid are all effective diagnostic indicators for peanut, wheat, and egg allergies, respectively.

Antigen-specific IgE can be a helpful biomarker for predicting clinical food allergy reactivity. Monitoring hen’s egg and cow’s milk-specific IgE levels can help predict prognosis, and baseline-specific IgE levels may be related to OIT results. The use of CRD gives us a more accurate tool for diagnosing food allergies.