Cutaneous carcinosarcoma is a rare type of biphasic tumor comprising malignant epithelial and heterologous mesenchymal elements. Data on the clinical and histopathologic characteristics of this tumor are scarce. The study aimed to describe the clinicopathologic and immunohistochemical features of cutaneous carcinosarcoma. A descriptive retrospective study was conducted in a tertiary care hospital from Spain. We reviewed the records of eight patients with cutaneous carcinosarcoma who were diagnosed from 2009 to 2019.

The average age of the patients at diagnosis was 72.13 years (range 44–91 years), and there was a male predilection (6 cases). The most common site of cutaneous carcinosarcoma was the head and neck (5 issues). Carcinosarcomas demonstrated variable histopathological and immunohistochemical features. Follow‐up was available for 7–8 patients. There were two cases of local recurrence and one case of metastasis. Two patients died from the tumor during the entire follow‐up. Although there was a limited number of cases in this study, The researchers’ results provide valuable points into the clinical, histopathologic, and immunohistochemical characteristics of primary cutaneous carcinosarcoma. However, the researchers and doctors are still doing more researchers on Primary cutaneous carcinosarcoma so that they can find a new way to treat the patients successfully.

Ref: https://onlinelibrary.wiley.com/doi/10.1111/ijd.14996