The prevalence of gastroenteritis has decreased significantly as a result of improving sanitary conditions in underdeveloped nations and the use of rotavirus vaccination. However, hundreds of children die each year from gastroenteritis, the majority of whom live in impoverished nations. However, gastroenteritis management is simple, cheap, and effective, and it is basically the same across the world. The therapy of gastroenteritis is guided by universal principles, which include basic therapies introduced early in the course of the disease. In chosen clinical circumstances associated with the symptoms or to host-related risk, therapy includes rehydration, continued oral feeding, and anti-infective medicines, as well as possible further pharmacological treatment to minimize the length and intensity of symptoms. Sanitation measures and rotavirus universal vaccination are advised for prevention. These interventions must be implemented in target regions through educational efforts and local programs.

A set of proposals for interventions, education, and research objectives aimed at decreasing the burden of gastroenteritis are given below, to be pursued by scientists, clinicians, policymakers, and others concerned. They include the need for guidelines for the treatment of gastroenteritis in malnourished children, individuals with chronic illnesses, newborns, and emergency situations. There is also a reference system for scoring dehydration, a description of the ideal composition of rehydration fluid, and indications for anti-infective therapy. Rotavirus vaccination should be aggressively pushed, and evidence-based protocols should be widely followed.