Due to the progress in health care facilities and research, life expectancy and the number of elderly people are progressively increasing. Allergic diseases also show an increasing incidence in geriatric age. This is partly due to the growing emphasis on a more accurate and careful diagnosis of the molecular mechanisms. It is still important because it do not allow us to ignore the real pathogenesis of many symptoms until now unknown and partly to the fact that the allergic people from 20 years ago represent the elderly population now.

Food contamination permits the onset of allergic diseases. This review was done to provide the state of the art on the physiological changes in the elderly responsible for allergic diseases, their biological characteristics, and the major immunological and extra immunological mechanisms. Emphasis is given to the management of several diseases in the elderly. Some new features are discussed for the purpose of a real and long-lasting benefit.

The study concluded through its findings that the mechanisms of adverse reactions to drugs are also discussed, due to their frequency at this age, especially in polytherapy regimens. Study of the modifications of the immune system is also of great importance.

Reference: https://clinicalmolecularallergy.biomedcentral.com/articles/10.1186/s12948-017-0059-2