When examining aortic valve stenosis (AS), researchers have frequently concentrated their attention on the effects of the condition on blood flow.  On the basis of hemodynamics and symptoms, interventional treatment for AS has been recommended; however, other parameters describing left ventricular and valvular and/or vascular remodeling were just as relevant for evaluating the prognosis and fate of individuals who have AS. The severity of AS in terms of its impact on hemodynamics was not reliably correlated with alterations in the left ventricle or valvular or vascular structures. These modifications in remodeling are mirrored in the heart muscle, and they can be discovered using cutting-edge diagnostic laboratory and imaging technologies. Examples of such diagnostic approaches include biomarkers, echocardiography, cardiac magnetic resonance, and gated computerized tomography (CT) imaging. When all of these are incorporated into the therapeutic decision-making process of the Heart Team, there is the potential for a significant improvement in the optimal patient selection for interventional treatment as well as patient outcomes for patients who have AS. Investigators discussed this innovative method and provided a straightforward procedure that the Heart Team can use to determine the best course of treatment for patients who have AS that ranges from mild to severe severity.

Source: sciencedirect.com/science/article/pii/S000287032200165X