Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for April 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Symptomatic Health Care Staff in U.K. Screened for COVID-19

THURSDAY, April 30, 2020 (HealthDay News) — Screening symptomatic health care workers for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is feasible during the pandemic, according to a research letter published online April 22 in The Lancet.

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Food Insecurity Rates High Amid COVID-19 Pandemic

THURSDAY, April 30, 2020 (HealthDay News) — Food insecurity in the United States is high as a result of the COVID-19 pandemic, according to a survey released April 23 by the University of Arkansas Community and Family Institute.

Press Release

Pediatric Brain Cancer Outcomes Worse for Black, Hispanic Patients

WEDNESDAY, April 29, 2020 (HealthDay News) — Treatment disparities may explain worse outcomes for pediatric black and Hispanic brain cancer patients, according to a study recently published in Scientific Reports.

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David Shulkin, M.D., on COVID-19 Financial Consequences for Health Care System

MONDAY, April 27, 2020 (HealthDay News) — Health care organizations are facing hard financial decisions amid the COVID-19 pandemic, but an end is in sight as some are beginning to slowly open back up around the country, according to David Shulkin, M.D. Shulkin, who served as ninth secretary for Veterans Affairs and is former president and CEO of Beth Israel Medical Center in New York, spoke with HealthDay during a live stream on the HealthDay YouTube channel and live blog.

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KIMT3 Article

USPSTF: Behavioral Interventions Likely Prevent Tobacco Use

WEDNESDAY, April 29, 2020 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) concludes that primary care-feasible behavioral interventions have a moderate net benefit for preventing tobacco use in children. These findings form the basis of a final recommendation statement, published online April 28 in the Journal of the American Medical Association.

Evidence Report (subscription or payment may be required)
Recommendations (subscription or payment may be required)
Editorial (subscription or payment may be required)

Major Depression Reduced for Those Reared in Adoptive Homes

WEDNESDAY, April 29, 2020 (HealthDay News) — Individuals at high risk for major depression reared in adoptive homes have a significantly reduced risk for major depression compared with those raised in their home environment, according to a study published online April 28 in the American Journal of Psychiatry.

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Nearly Half of U.S. Population Breathes Unhealthy Air

TUESDAY, April 28, 2020 (HealthDay News) — Climate change continues to make air pollution worse, with 45.8 percent of the U.S. population living in counties with unhealthy ozone or particle pollution, according to the American Lung Association (ALA) 21st annual State of the Air report.

State of the Air Report

Rare, Serious Illness May Occur in Children With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) — Abdominal pain, gastrointestinal complaints, and heart inflammation are among the symptoms in children with a rare syndrome that may be linked to COVID-19, British health officials say.

CNN Article

Roadmap Developed for Resuming Elective Surgery During COVID-19

MONDAY, April 27, 2020 (HealthDay News) — A roadmap for resuming elective surgery after new cases of COVID-19 begin to wane is presented in a joint statement published by the American College of Surgeons and other societies.

Joint Statement

FDA Bans Products That Help Kids Hide Vape Use From Parents

MONDAY, April 27, 2020 (HealthDay News) — On Monday, the U.S. Food and Drug Administration announced it was sending warning letters to 10 manufacturers to stop making products designed to allow youth to vape without getting caught by parents or teachers.

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FDA Warns of Bogus Claims by Makers of Hand Sanitizer

MONDAY, April 27, 2020 (HealthDay News) — Some companies are selling hand sanitizers with unproven claims that they will protect against COVID-19, the U.S. Food and Drug Administration warns.

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WHO: No Evidence COVID-19 Survivors Cannot Be Reinfected

MONDAY, April 27, 2020 (HealthDay News) — There is “no evidence” that people who have recovered from COVID-19 cannot be reinfected with the severe acute respiratory syndrome coronavirus 2, according to the World Health Organization.

CBS News Article
CNN Article
More Information: CDC

Racial Differences Found in Managing Children’s Pain From Broken Bones

MONDAY, April 27, 2020 (HealthDay News) — There are racial differences in pain management and pain outcomes for children seen in the emergency department for long-bone fractures, according to a study published online April 20 in Pediatrics.

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Pulse Oximetry May Be Overused in Infants With Bronchiolitis

MONDAY, April 27, 2020 (HealthDay News) — Use of monitoring with continuous pulse oximetry for infants with bronchiolitis who do not require supplemental oxygen varies widely by hospital, according to a study published in the April 21 issue of the Journal of the American Medical Association.

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Direct Medical Costs of COVID-19 Infection Are Considerable

MONDAY, April 27, 2020 (HealthDay News) — A single symptomatic COVID-19 infection results in direct medical costs of $3,045 in the United States, according to a study published online April 23 in Health Affairs.

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Recommendations Issued for Imaging Use in Pediatric COVID-19

MONDAY, April 27, 2020 (HealthDay News) — In an international expert consensus statement, published online April 23 in Radiology: Cardiothoracic Imaging, recommendations are presented for chest imaging in pediatric COVID-19 patient management.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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COVID-19 Pandemic Delays FDA Review of Vaping Products

FRIDAY, April 24, 2020 (HealthDay News) — A review of vaping products has been delayed by the COVID-19 outbreak, the U.S. Food and Drug Administration announced Thursday.

AP News Article

More Than One in Five Children in Home Confinement Report Depression

FRIDAY, April 24, 2020 (HealthDay News) — During the COVID-19 outbreak in Hubei province in China, 22.6 percent of children in home confinement reported depressive symptoms, according to a research letter published online April 24 in JAMA Pediatrics.

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Review: MMR, MMRV, MMR+V Vaccines Are Effective, Safe

FRIDAY, April 24, 2020 (HealthDay News) — Measles, mumps, and rubella (MMR) vaccines and MMR vaccines with varicella are effective and safe, according to an updated review published online April 20 in the Cochrane Database of Systematic Reviews.

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Low Doses of Bevacizumab Tested for Retinopathy of Prematurity

FRIDAY, April 24, 2020 (HealthDay News) — For treatment of retinopathy of prematurity (ROP), 0.004 mg may be the lowest effective dose of bevacizumab, according to a study published online April 23 in JAMA Ophthalmology.

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Vegetable Intake Before Pregnancy Tied to Birth Outcomes

FRIDAY, April 24, 2020 (HealthDay News) — Greater vegetable intake before pregnancy is associated with better birth outcomes, according to a study published online April 13 in The American Journal of Clinical Nutrition.

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‘Health Force’ to Combat Pandemic Proposed by U.S. Senators

THURSDAY, April 23, 2020 (HealthDay News) — A bill to create a “Health Force” to help combat the U.S. COVID-19 outbreak has been announced by two Democratic senators.

NBC News Article

CDC: More Chemical Exposures Reported in January to March 2020

THURSDAY, April 23, 2020 (HealthDay News) — In January to March 2020, there were more chemical exposures reported to the National Poison Data System than in the corresponding months of 2019 and 2018, according to research published in the April 20 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Mild, No Symptoms Seen for Most Children With SARS-CoV-2 Infection

THURSDAY, April 23, 2020 (HealthDay News) — Most children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have mild respiratory symptoms or are asymptomatic, according to a review published online April 22 in JAMA Pediatrics.

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Clascoterone Cream Safe, Effective for Acne Treatment

THURSDAY, April 23, 2020 (HealthDay News) — Clascoterone cream, 1 percent, appears to be safe and effective for the treatment of acne, according to a study published online April 22 in JAMA Dermatology.

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Editorial

Firework-Related ED Visits Peak Around Independence Day

WEDNESDAY, April 22, 2020 (HealthDay News) — Most emergency department admissions for firework-related injuries occur near Independence Day and New Year’s Day, involve men and people younger than 18, and are caused by firecrackers and bottle rockets, according to a study published online April 9 in JAMA Ophthalmology.

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Scoring System Helps Guide Surgical Care During COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) — A scoring system for medically necessary time-sensitive (MeNTS) procedures can facilitate decision making and triage in the setting of COVID-19, according to a study published online April 9 in the Journal of the American College of Surgeons.

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USPSTF Notes Evidence Lacking for BP Screening in Children

TUESDAY, April 21, 2020 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) concludes that there is currently insufficient evidence to evaluate the balance of benefits and harms of screening children and adolescents for high blood pressure. These findings form the basis of a draft recommendation statement, published April 21 by the USPSTF.

Draft Evidence Review
Draft Recommendation Statement
Comment on Recommendation Statement

LA County COVID-19 Infections Far Exceed Number of Confirmed Cases

TUESDAY, April 21, 2020 (HealthDay News) — An early analysis of antibody testing from Los Angeles County reveals a COVID-19 infection rate that is up to 55 times the number of confirmed COVID-19 cases.

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Mental Health Consequences of COVID-19 Pandemic Explored

TUESDAY, April 21, 2020 (HealthDay News) — A new position paper, published online April 15 in The Lancet Psychiatry, highlights the mental health consequences of COVID-19 management.

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176,190 U.S. Children Estimated to Have SARS-CoV-2 by April 6, 2020

TUESDAY, April 21, 2020 (HealthDay News) — About 176,190 children nationwide were estimated to be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by April 6, 2020, according to a study published online April 16 in the Journal of Public Health Management & Practice.

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More Screen Time for Babies Tied to Autism-Like Symptoms

TUESDAY, April 21, 2020 (HealthDay News) — Greater screen exposure and less interactive play between caregivers and children early in life is associated with autism spectrum disorder (ASD)-like symptoms at age 2 years, according to a study published online April 20 in JAMA Pediatrics.

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Smoking Only in Early Pregnancy Still Puts Baby at Risk

TUESDAY, April 21, 2020 (HealthDay News) — While quitting smoking during the first trimester slightly decreases the risk for low birth weight in newborns, any duration of maternal smoking during pregnancy is associated with low birth weight and abnormal body proportions, according to a study recently published in BMJ Open.

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Public Health Measures Cut COVID-19 Transmission in Hong Kong

MONDAY, April 20, 2020 (HealthDay News) — Public health measures implemented to suppress local transmission of COVID-19 in Hong Kong were associated with reduced transmission of COVID-19 and influenza, according to a study published online April 17 in The Lancet Public Health.

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Hypertension in Pregnancy Ups Risk for Mental Disorder in Child

MONDAY, April 20, 2020 (HealthDay News) — Maternal hypertensive pregnancy disorders are associated with increased risk in offspring for any childhood mental disorder, according to a study published online April 20 in Hypertension.

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AAP Updates Guidance for Care of Infants Born at Home

MONDAY, April 20, 2020 (HealthDay News) — In an American Academy of Pediatrics (AAP) policy statement, published online April 20 in Pediatrics, recommendations are presented for the care of newborn infants immediately after birth and in the transition and subsequent period after home birth.

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Benefit of Social Distancing Outweighs Economic Impact

MONDAY, April 20, 2020 (HealthDay News) — The economic benefits of lives saved through social distancing substantially outweigh the value of the projected losses to the U.S. economy, according to a study to be published in a forthcoming issue of the Journal of Benefit-Cost Analysis.

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Child Obesity Linked to Higher Mortality Risk in Young Adulthood

MONDAY, April 20, 2020 (HealthDay News) — Obesity in children is associated with an increased risk for premature mortality in young adulthood and with an increased risk for anxiety and depression, according to two studies published online in March in PLOS Medicine and BMC Medicine.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 13 to 17, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Incidence of SARS-CoV-2 Infection Stable in Iceland

FRIDAY, April 17, 2020 (HealthDay News) — In Iceland, the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was stable through 20 days of screening, according to a study published online April 14 in the New England Journal of Medicine.

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Asthma Not Common in COVID-19 Patients Who Have Died

FRIDAY, April 17, 2020 (HealthDay News) — Asthma is not among the top 10 chronic health problems in people who have died from coronavirus disease 2019 (COVID-19) in New York state, even though many health experts have warned that people with asthma are at increased risk for severe illness if they get COVID-19.

The New York Times Article

IDSA Issues Rapid Guidelines for Treatment of COVID-19

FRIDAY, April 17, 2020 (HealthDay News) — In rapid guidelines issued by the Infectious Diseases Society of America (IDSA), recommendations are presented for the treatment and management of coronavirus disease 2019 (COVID-19).

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Removal of Flavored E-Cigarette Products Likely Ineffective

FRIDAY, April 17, 2020 (HealthDay News) — Juul sales recovered within weeks following a dip after the company withdrew some flavored products from stores, even surpassing sales before the withdraw, according to a study published online April 16 in the American Journal of Public Health.

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Probiotics May Help Reduce Mild-to-Moderate Acne Symptoms

FRIDAY, April 17, 2020 (HealthDay News) — The use of probiotics as an adjunct therapy may help in the management of acne vulgaris, according to a review published online April 7 in Dermatologic Therapy.

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Recurrent Winter Outbreaks of SARS-CoV-2 Projected

THURSDAY, April 16, 2020 (HealthDay News) — Recurrent winter outbreaks of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are projected to occur after the initial pandemic wave, according to a study published online April 14 in Science.

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Uninsurance for Poor New Moms Down With ACA Medicaid Expansion

THURSDAY, April 16, 2020 (HealthDay News) — Among new mothers living in poverty, the Affordable Care Act (ACA) Medicaid expansion was associated with a reduction in uninsurance and increased Medicaid coverage, according to a study published online April 15 in Pediatrics.

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Prevalence of Autoimmunity May Be on the Rise

THURSDAY, April 16, 2020 (HealthDay News) — The prevalence of antinuclear antibodies (ANA) in the United States has increased considerably between 1988 and 2012, according to a study published online April 7 in Arthritis & Rheumatology.

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Survey Shows Lack of COVID-19 Concern Even Among Those at Risk

WEDNESDAY, April 15, 2020 (HealthDay News) — Many individuals at greater risk for coronavirus disease 2019 (COVID-19) complications did not believe the virus would affect them at the beginning of Chicago’s outbreak, according to a study published online April 9 in the Annals of Internal Medicine.

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SARS-CoV-2 Contamination of Air, Surfaces Examined in ICU, Wards

WEDNESDAY, April 15, 2020 (HealthDay News) — Considerable severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) contamination of air and object surfaces is reported in intensive care units (ICUs) and general coronavirus disease 2019 (COVID-19) wards (GW), according to a study published online April 10 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

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Public Health Interventions Improved COVID-19 Control in Wuhan

WEDNESDAY, April 15, 2020 (HealthDay News) — Multifaceted public health interventions improved control of the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, according to a study published online April 10 in the Journal of the American Medical Association.

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Editorial

Common Coronaviruses Are Highly Seasonal

WEDNESDAY, April 15, 2020 (HealthDay News) — Common coronaviruses circulate seasonally, according to a study published online April 4 in the Journal of Infectious Diseases.

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Review: Quarantine Effective for Reducing Infection, Death

TUESDAY, April 14, 2020 (HealthDay News) — Quarantine is effective for reducing the number of people infected and deaths from coronavirus disease 2019 (COVID-19), according to a review published online April 8 in the Cochrane Database of Systematic Reviews.

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CDC: Public Policy Measures Important for Social Distancing

TUESDAY, April 14, 2020 (HealthDay News) — Community mobility in four metropolitan areas decreased with the introduction of public policy measures supporting social distancing, which could help slow the spread of coronavirus disease 2019 (COVID-19), according to research published in the April 13 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Medical Masks May Be Sufficient During COVID-19 Routine Care

TUESDAY, April 14, 2020 (HealthDay News) — Use of medical masks, such as surgical or procedural masks, does not increase the risk for viral infection or respiratory illness, and their use may serve as a protective measure in instances of N95 respirator shortages, according to the results of a meta-analysis published online April 4 in Influenza and Other Respiratory Viruses.

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First Wave of COVID-19 Abated With Control Measures in China

TUESDAY, April 14, 2020 (HealthDay News) — Interventions implemented in China interrupted coronavirus disease 2019 (COVID-19) transmission in all areas outside of Hubei, and low transmissibility can be maintained by monitoring the instantaneous effective reproduction number (Rt), according to a study published online April 8 in The Lancet.

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Overweight, Obese Preschoolers Have Higher Risk for Fractures

TUESDAY, April 14, 2020 (HealthDay News) — Preschool children with a body mass index (BMI) in the overweight or obese range have an increased incidence of bone fractures in childhood compared with preschool children of normal weight, according to a study published online April 7 in the Journal of Bone and Mineral Research.

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High Rates of Appropriate E-Consults Seen Across Specialties

MONDAY, April 13, 2020 (HealthDay News) — The rates of appropriate electronic consultations (e-consults) are high across specialties, according to a study published online April 14 in the Annals of Internal Medicine.

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CDC Report Details Geographic Variation in U.S. COVID-19 Cases, Deaths

MONDAY, April 13, 2020 (HealthDay News) — There is variation in the cumulative incidence of coronavirus disease 2019 (COVID-19) across jurisdictions in the United States, according to research published in the April 10 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Guidance Issued for Infants Born to Mothers With COVID-19

MONDAY, April 13, 2020 (HealthDay News) — In an initial guidance document issued by the American Academy of Pediatrics, recommendations are presented for the management of infants born to mothers with suspected or confirmed coronavirus disease 2019 (COVID-19).

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 6 to 10, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Contact Tracing ID’d Large Multifamily COVID-19 Cluster in Chicago

FRIDAY, April 10, 2020 (HealthDay News) — One index patient with COVID-19 and only mild symptoms attended two family gatherings and likely triggered a chain of transmission that included 15 other confirmed and probable cases with three deaths, according to research published in the April 8 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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FDA Approves New Way to Decontaminate N95 Face Masks

FRIDAY, April 10, 2020 (HealthDay News) — The second emergency use authorization to decontaminate N95 face masks and equivalents for reuse by hospital health care workers has been issued by the U.S. Food and Drug Administration.

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Temperature, UV Radiation Not Linked to Incidence of COVID-19

FRIDAY, April 10, 2020 (HealthDay News) — Ambient temperature and ultraviolet (UV) radiation are not associated with the cumulative incidence rate or basic reproduction number (R0) of coronavirus disease 2019 (COVID-19), according to a research letter published online April 8 in the European Respiratory Journal.

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Neurologic Effects Seen in a Third of Hospitalized COVID-19 Patients

FRIDAY, April 10, 2020 (HealthDay News) — Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.

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Doctors Report on Four COVID-19 Infections in Newborns in China

FRIDAY, April 10, 2020 (HealthDay News) — Compared with adults, symptoms of COVID-19 in newborn babies are milder and outcomes are less severe, according to a research letter published online April 8 in the European Respiratory Journal.

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Current Models for COVID-19 Diagnosis, Prognosis Unreliable

FRIDAY, April 10, 2020 (HealthDay News) — Novel coronavirus (COVID-19)-related models that are published in the literature are poorly reported and at high risk for bias, raising concern that their predictions could be unreliable when applied in daily practice, according to a review published online April 7 in The BMJ.

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Face Masks Offer Slight Protective Effect From Flu-Like Illness

FRIDAY, April 10, 2020 (HealthDay News) — Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact, according to a review that has not yet been peer reviewed and was posted online April 6 at medRxiv.org.

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Anxiety Up for Nonmedical Health Care Workers Versus Those on Front Lines

FRIDAY, April 10, 2020 (HealthDay News) — Non-medically trained health care workers caring for patients with coronavirus disease 2019 (COVID-19) have an increased prevalence of anxiety compared with medically trained health care workers, according to a research letter published online April 6 in the Annals of Internal Medicine.

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Nocturnal Supervision May Have Protective Effect in SUDEP

FRIDAY, April 10, 2020 (HealthDay News) — There is limited, very low-certainty evidence of a protective effect for nocturnal supervision against sudden unexpected death in epilepsy (SUDEP), according to a report published online April 2 in the Cochrane Database of Systematic Reviews.

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Adult Smoking, Cessation Tied to Smoking Intensity in Adolescence

FRIDAY, April 10, 2020 (HealthDay News) — The prevalence rates of smoking and cessation in adulthood are associated with levels of childhood smoking intensity, according to a study published in the April 9 issue of the Journal of the American Heart Association.

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Clinical Trial Underway to Test Nitric Oxide in COVID-19 Patients

THURSDAY, April 9, 2020 (HealthDay News) — Doctors at the University of Alabama at Birmingham (UAB) are enrolling patients in an international clinical trial to find out if inhaled nitric oxide benefits those with novel coronavirus (COVID-19) who have severely damaged lungs.

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COVID-19 Came to New York City From Europe, Not Asia

THURSDAY, April 9, 2020 (HealthDay News) — The novel coronavirus (COVID-19) has been circulating in New York City for longer than previously believed and most cases can be traced back to Europe, new research reveals.

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Johns Hopkins University

FDA Warns of False Claims That Chlorine Dioxide Can Treat COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — A warning letter has been sent to a company marketing fraudulent and dangerous chlorine dioxide products for the prevention and treatment of the novel coronavirus (COVID-19), the U.S. Food and Drug Administration says.

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Another COVID-19 Vaccine Trial Begins in the United States

THURSDAY, April 9, 2020 (HealthDay News) — Another clinical trial of an experimental vaccine for the novel coronavirus 2019 (COVID-19) has been launched by U.S. researchers.

AP News Article

Prognosis Poor for Pediatric, Adolescent Patients With Colon Cancer

TUESDAY, April 7, 2020 (HealthDay News) — Patients with colon cancer who are younger than 25 years have a higher risk for death compared with older adults, according to a retrospective review published in the April issue of the Journal of the American College of Surgeons.

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HHS Report Looks at Hospital Experiences With COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — A report issued by the U.S. Department of Health and Human Services Office of Inspector General provides a national snapshot of hospital experiences in response to the coronavirus disease 2019 (COVID-19).

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ATS Provides Interim Guidance for Management of COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — In a guidance document issued by the American Thoracic Society, interim recommendations are presented for management of coronavirus disease 2019 (COVID-19).

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Parents’ Mental Illness Tied to Higher Injury Rate in Offspring

THURSDAY, April 9, 2020 (HealthDay News) — Parental mental illness is associated with an increased risk for injuries among offspring, especially during the first year of the child’s life, according to a study published online April 8 in The BMJ.

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CDC Removes Prescribing Guidelines for Antimalarial Drugs

WEDNESDAY, April 8, 2020 (HealthDay News) — Guidelines for doctors on how to prescribe two antimalarial drugs that some believe may treat the novel coronavirus (COVID-19) are no longer available on the U.S. Centers for Disease Control and Prevention website.

CNN Article
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Johns Hopkins University

Children With COVID-19 Do Not Always Have Cough, Fever

WEDNESDAY, April 8, 2020 (HealthDay News) — Children with coronavirus disease 2019 (COVID-19) have symptoms of fever, cough, or shortness of breath less often than adults with the disease, according to research published in the April 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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CDC: 1999 to 2018 Saw 35 Percent Increase in Suicide Rates

WEDNESDAY, April 8, 2020 (HealthDay News) — Suicide rates increased 35 percent from 1999 through 2018, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Surgical, Cotton Masks Not Effective for Filtering SARS-CoV-2

WEDNESDAY, April 8, 2020 (HealthDay News) — For patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), neither surgical nor cotton masks effectively filter SARS-CoV-2 during coughs, according to a research letter published online April 6 in the Annals of Internal Medicine.

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Maternal Obesity May Be Related to Risk for ADHD in Children

WEDNESDAY, April 8, 2020 (HealthDay News) — Mothers with a body mass index (BMI) of 25 kg/m² and greater are more likely to see behavioral problems and psychiatric symptoms in their children, according to a study recently published in The Journal of Pediatrics.

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Children Have Milder Disease Course, Better COVID-19 Prognosis

WEDNESDAY, April 8, 2020 (HealthDay News) — Children diagnosed with COVID-19 have a milder disease course and better prognoses than adults, according to a review published online March 23 in Acta Paediatrica.

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Side Effects Seen With Use of Chloroquine Against COVID-19

TUESDAY, April 7, 2020 (HealthDay News) — The use of the antimalarial drug chloroquine to treat COVID-19 patients has been halted at several Swedish hospitals due to reported side effects such as cramps and loss of peripheral vision. Sahlgrenska University Hospital is one of those facilities. It stopped the use of chloroquine in the treatment of COVID-19 about two weeks ago.

Newsweek Article
Johns Hopkins University

School Closures Could Further Complicate COVID-19 Effort

TUESDAY, April 7, 2020 (HealthDay News) — Potential contagion prevention from school closures needs to be weighed against the potential loss of health care workers due to child care obligations during the coronavirus disease 2019 (COVID-19) pandemic, according to a study published online April 3 in The Lancet Public Health.

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No Treatment Change Needed for Peds IBD During COVID-19 Pandemic

TUESDAY, April 7, 2020 (HealthDay News) — Preliminary data regarding outcomes for pediatric patients with inflammatory bowel disease (IBD) during the coronavirus disease 2019 (COVID-19) outbreak are reassuring, according to research published online March 31 in the Journal of Pediatric Gastroenterology and Nutrition.

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Early-Life Mortality Risk Higher in ART-Conceived Children

TUESDAY, April 7, 2020 (HealthDay News) — Compared with children who are naturally conceived, children who are conceived via assisted reproductive techniques (ART) may be at increased risk for mortality during their first year of life, according to a study published in the March issue of Fertility and Sterility.

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‘Mod’ E-Cigarette Users Smoke More Cigarettes One Year Later

TUESDAY, April 7, 2020 (HealthDay News) — Baseline modifiable (mod) electronic cigarette device users smoke more cigarettes at one-year follow-up than vape pen users, according to a study published online April 6 in Pediatrics.

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Majority of Physicians Report Serious Concerns About COVID-19

MONDAY, April 6, 2020 (HealthDay News) — According to a national survey conducted by Harvard Medical School, the RAND Corporation, and Doximity, practicing physicians currently report substantial concerns about supplies, the government response, and availability of testing amid the COVID-19 pandemic.

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FDA Authorizes Use of Chinese-Approved Masks in United States

MONDAY, April 6, 2020 (HealthDay News) — Emergency use authorization of protective masks that do not meet American standards has been announced by the U.S. Food and Drug Administration.

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Sentinel Surveillance Can Help Monitor Epidemiology of COVID-19

MONDAY, April 6, 2020 (HealthDay News) — Rapid sentinel surveillance can help monitor the epidemiology of coronavirus disease 2019 (COVID-19), according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Comorbidity, Age, Time to Treatment Linked to COVID-19 Progression

MONDAY, April 6, 2020 (HealthDay News) — Factors associated with coronavirus disease 2019 (COVID-19) progression include comorbidity, age, and time from illness onset to antiviral treatment, according to a study published online March 27 in the Journal of Internal Medicine.

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Hydroxychloroquine Can Shorten Time to Recovery in COVID-19

MONDAY, April 6, 2020 (HealthDay News) — Hydroxychloroquine (HCQ) can shorten time to clinical recovery and promote pneumonia absorption among patients with coronavirus disease 2019 (COVID-19), according to a study that has not yet been peer reviewed and was posted online March 31 at medRxiv.org.

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Brain Changes From Multiple Sclerosis May Occur in Preteens

MONDAY, April 6, 2020 (HealthDay News) — Greater genetic predisposition for multiple sclerosis (MS) is associated with altered brain white matter development at an early age, according to a study published online March 12 in the Annals of Neurology.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 30 to April 3, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice

FRIDAY, April 3, 2020 (HealthDay News) — Microneedle array (MNA) delivery of trimeric coronavirus spike (S) protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to research published online April 2 in EBioMedicine.

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Presymptomatic Transmission of SARS-CoV-2 ID’d in Singapore

FRIDAY, April 3, 2020 (HealthDay News) — Presymptomatic transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been observed in epidemiological clusters in Singapore, with transmission occurring one to three days before symptom onset, according to research published in the April 1 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Model Projects COVID-19 Deaths in Italy Through Mid-April

FRIDAY, April 3, 2020 (HealthDay News) — Modeling suggests that in Italy, the number of coronavirus disease 2019 (COVID-19) intensive care unit (ICU) patients will continue increasing into April, according to a report published April 1 by the European Society of Anaesthesiology.

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Autism Rates Inversely Tied to County’s Wealth

FRIDAY, April 3, 2020 (HealthDay News) — Rates of autism spectrum disorders (ASD) are declining among wealthy whites in California while escalating among poor and minority children, according to a study published online March 19 in the Journal of Autism and Developmental Disorders.

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Amid COVID-19 Crisis, Blood Donor Restrictions Eased

FRIDAY, April 3, 2020 (HealthDay News) — America is in urgent need of blood donations during the COVID-19 pandemic, so the U.S. Food and Drug Administration said Thursday it will relax donor restrictions placed on gay and bisexual men and others.

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Gastrointestinal Symptoms Common in COVID-19 Patients

FRIDAY, April 3, 2020 (HealthDay News) — Gastrointestinal symptoms are common in patients with coronavirus disease 2019 (COVID-19), with increased prevalence seen in the later stages of the epidemic in China, according to a review published online March 29 in Alimentary Pharmacology & Therapeutics.

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Unemployed Workers Less Likely to Be Uninsured Post-ACA

THURSDAY, April 2, 2020 (HealthDay News) — Following implementation of the Affordable Care Act (ACA), unemployed workers were less likely to be uninsured, and uninsurance rates decreased more in states with Medicaid expansion, according to a report from the Urban Institute and the Robert Wood Johnson Foundation.

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Proton Pump Inhibitor Therapy May Up Fracture Risk in Children

THURSDAY, April 2, 2020 (HealthDay News) — Proton pump inhibitors (PPIs) taken for acid reflux may lead to an increased risk for fractures in children and adolescents, according to a study published online March 12 in the Journal of Pediatric Gastroenterology and Nutrition.

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Risk Factors for Missed Appendicitis Diagnosis Identified

THURSDAY, April 2, 2020 (HealthDay News) — Certain patient and presentation factors increase the likelihood of a missed appendicitis diagnosis in the emergency department, according to a study published online March 9 in JAMA Network Open.

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Transmission Control Measures Tied to Delay in COVID-19 Growth

THURSDAY, April 2, 2020 (HealthDay News) — Transmission control measures implemented in Wuhan were associated with a delay in epidemic growth during the first 50 days of the coronavirus disease 2019 (COVID-19) epidemic in China, according to a study published online March 31 in Science.

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Imported Masks, Other Medical Supplies Arriving in U.S.

WEDNESDAY, April 1, 2020 (HealthDay News) — For the first time since February, imported N95 medical masks are arriving in the United States, but they are not nearly enough to meet demand as COVID-19 cases climb.

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Burden of Childhood Cancer Can Be Diminished

WEDNESDAY, April 1, 2020 (HealthDay News) — The burden of childhood cancer can be effectively diminished to realize health and economic benefits, according to research published in the April 1 issue of The Lancet Oncology.

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Ocular Abnormalities Seen in One-Third of COVID-19 Patients

WEDNESDAY, April 1, 2020 (HealthDay News) — About one-third of patients with coronavirus disease 2019 (COVID-19) have ocular abnormalities, according to a brief report published online March 31 in JAMA Ophthalmology.

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Persistent Positive SARS-CoV-2 Found in Sputum, Feces Samples

WEDNESDAY, April 1, 2020 (HealthDay News) — Some patients with coronavirus disease 2019 (COVID-19) remain positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in sputum or feces after pharyngeal samples become negative, according to a research letter published online March 30 in the Annals of Internal Medicine.

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Four Trajectories of Peer Victimization ID’d Across Childhood

WEDNESDAY, April 1, 2020 (HealthDay News) — There are four developmental patterns of peer victimization across childhood, and family vulnerabilities are associated with development of distinct trajectories, according to a study published online April 1 in Pediatrics.

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ENDO: Liraglutide May Benefit Adolescents With Obesity

WEDNESDAY, April 1, 2020 (HealthDay News) — Liraglutide plus lifestyle therapy results in a significantly greater reduction in body mass index (BMI) standard-deviation score than placebo among adolescents with obesity, according to a study published online March 31 in the New England Journal of Medicine to coincide with the virtual meeting of The Endocrine Society, held from March 28 to 31.

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Patients With Mild COVID-19 May Present With Digestive Symptoms

WEDNESDAY, April 1, 2020 (HealthDay News) — Patients with mild coronavirus disease 2019 (COVID-19) can present with digestive symptoms, sometimes without concurrent fever, according to a study published online March 30 in the American Journal of Gastroenterology.

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