Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for April 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Symptomatic Health Care Staff in U.K. Screened for COVID-19

THURSDAY, April 30, 2020 (HealthDay News) — Screening symptomatic health care workers for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is feasible during the pandemic, according to a research letter published online April 22 in The Lancet.

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Remdesivir May Accelerate Recovery From Severe COVID-19

THURSDAY, April 30, 2020 (HealthDay News) — Remdesivir may speed time to clinical improvement for patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, although results are conflicting, according to a study published online April 29 in The Lancet and press releases issued regarding a National Institutes of Health (NIH)-sponsored study.

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Editorial (subscription or payment may be required)
Press Release

Men Have More Serious Disease, Higher Death Rate From COVID-19

THURSDAY, April 30, 2020 (HealthDay News) — For patients with COVID-19, male gender is associated with worse outcomes, independent of age, according to a study published online April 29 in Frontiers in Public Health.

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14.9 Percent of U.S. Adults Had Ever Used an E-Cigarette in 2018

THURSDAY, April 30, 2020 (HealthDay News) — In 2018, 14.9 percent of U.S. adults had ever used an electronic cigarette (e-cigarette) and 3.2 percent were current users, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Smoking Tied to Inferior Survival in Acute Myeloid Leukemia

WEDNESDAY, April 29, 2020 (HealthDay News) — Smoking status is an important patient-related prognostic factor for outcome in patients with acute myeloid leukemia (AML) treated with intensive chemotherapy, according to a study published online April 21 in the British Journal of Haematology.

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Guidelines Recommended for ECMO Use in Setting of Pandemic

WEDNESDAY, April 29, 2020 (HealthDay News) — Hospitals should have a formal plan to respond to the increasing need for extracorporeal membrane oxygenation (ECMO) in the setting of a pandemic such as COVID-19, according to a study published online April 15 in the Annals of the American Thoracic Society.

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David Shulkin, M.D., on COVID-19 Financial Consequences for Health Care System

MONDAY, April 27, 2020 (HealthDay News) — Health care organizations are facing hard financial decisions amid the COVID-19 pandemic, but an end is in sight as some are beginning to slowly open back up around the country, according to David Shulkin, M.D. Shulkin, who served as ninth secretary for Veterans Affairs and is former president and CEO of Beth Israel Medical Center in New York, spoke with HealthDay during a live stream on the HealthDay YouTube channel and live blog.

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KIMT3 Article

Thromboembolic Complications in COVID-19 Discussed

WEDNESDAY, April 29, 2020 (HealthDay News) — Prevention, diagnosis, and therapeutic management of thromboembolic complications in COVID-19 are discussed in a report published online April 23 in Radiology.

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Nearly Half of U.S. Population Breathes Unhealthy Air

TUESDAY, April 28, 2020 (HealthDay News) — Climate change continues to make air pollution worse, with 45.8 percent of the U.S. population living in counties with unhealthy ozone or particle pollution, according to the American Lung Association (ALA) 21st annual State of the Air report.

State of the Air Report

National Coronavirus Testing Strategy Announced as U.S. Cases Top 1 Million

TUESDAY, April 28, 2020 (HealthDay News) — While health experts continued to call for a national strategy to test more Americans for coronavirus, President Donald Trump on Monday announced a “blueprint” for boosting testing capacity as some states began reopening their economies.

Washington Post Article
CBS News Article
New York Times Article

High Rate of Pulmonary Embolism Found for Patients With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) — COVID-19 is associated with a high rate of pulmonary embolism, according to two research letters published online April 23 in Radiology.

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Adding High-Dose Chloroquine Not Advised for Severe COVID-19

TUESDAY, April 28, 2020 (HealthDay News) — High-dosage chloroquine diphosphate (CQ) has potential safety hazards when used as adjunctive therapy for patients hospitalized with severe COVID-19, according to a study published online April 24 in JAMA Network Open.

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Editorial

45.4 Percent of U.S. Adults at Risk for Complications With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) — An estimated 45.4 percent of U.S. adults may have an increased risk for COVID-19 complications due to chronic conditions, according to a study published in the August issue of Emerging Infectious Diseases.

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Neurologic Features Tied to ARDS in Severe COVID-19 Described

MONDAY, April 27, 2020 (HealthDay News) — Acute respiratory distress syndrome (ARDS) due to COVID-19 is associated with neurologic features, including encephalopathy, agitation, and confusion, according to a letter to the editor published online April 15 in the New England Journal of Medicine.

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Roadmap Developed for Resuming Elective Surgery During COVID-19

MONDAY, April 27, 2020 (HealthDay News) — A roadmap for resuming elective surgery after new cases of COVID-19 begin to wane is presented in a joint statement published by the American College of Surgeons and other societies.

Joint Statement

WHO: No Evidence COVID-19 Survivors Cannot Be Reinfected

MONDAY, April 27, 2020 (HealthDay News) — There is “no evidence” that people who have recovered from COVID-19 cannot be reinfected with the severe acute respiratory syndrome coronavirus 2, according to the World Health Organization.

CBS News Article
CNN Article
More Information: CDC

Pulse Oximetry May Be Overused in Infants With Bronchiolitis

MONDAY, April 27, 2020 (HealthDay News) — Use of monitoring with continuous pulse oximetry for infants with bronchiolitis who do not require supplemental oxygen varies widely by hospital, according to a study published in the April 21 issue of the Journal of the American Medical Association.

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Recommendations Issued for Imaging Use in Pediatric COVID-19

MONDAY, April 27, 2020 (HealthDay News) — In an international expert consensus statement, published online April 23 in Radiology: Cardiothoracic Imaging, recommendations are presented for chest imaging in pediatric COVID-19 patient management.

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Direct Medical Costs of COVID-19 Infection Are Considerable

MONDAY, April 27, 2020 (HealthDay News) — A single symptomatic COVID-19 infection results in direct medical costs of $3,045 in the United States, according to a study published online April 23 in Health Affairs.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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HTN, Obesity, Diabetes Common in U.S. COVID-19 Patients

FRIDAY, April 24, 2020 (HealthDay News) — The most common comorbidities among patients hospitalized with COVID-19 in the New York City area are hypertension, obesity, and diabetes, according to a study published online April 22 in the Journal of the American Medical Association.

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COVID-19 Pandemic Delays FDA Review of Vaping Products

FRIDAY, April 24, 2020 (HealthDay News) — A review of vaping products has been delayed by the COVID-19 outbreak, the U.S. Food and Drug Administration announced Thursday.

AP News Article

Premature Posting of Remdesivir Findings Were ‘Inconclusive’

FRIDAY, April 24, 2020 (HealthDay News) — Inconclusive findings from a study investigating the antiviral drug remdesivir as a treatment for COVID-19 were posted to the World Health Organization website “prematurely,” drug maker Gilead Sciences said Thursday.

CNN Article

FDA Warns About Treating COVID-19 With Unproven Drugs

FRIDAY, April 24, 2020 (HealthDay News) — Malaria drugs touted by some as potential “game changers” against COVID-19 are actually too dangerous for general use, the U.S. Food and Drug Administration warned Americans on Friday.

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COVID-19-Linked Changes Reported in Rheumatic Disease Patient Care

FRIDAY, April 24, 2020 (HealthDay News) — Changes to health care have been reported among patients with rheumatic diseases during the COVID-19 pandemic, according to a study published online April 20 in ACR: Open Rheumatology.

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SARS-CoV-2 Stays in Respiratory Samples Longer in Severely Ill

FRIDAY, April 24, 2020 (HealthDay News) — The median duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is significantly longer in the respiratory samples of patients with severe versus mild disease, according to a study published online April 21 in The BMJ.

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Infection Rate Up Prior to Detection of Malignant Cancer

FRIDAY, April 24, 2020 (HealthDay News) — The rate of infection with influenza, gastroenteritis, hepatitis, and pneumonia is increased before detection of malignant cancer, according to a study published online April 17 in Cancer Immunology Research.

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Survey Finds Anesthesiologists Prepared for COVID-19 Patients

FRIDAY, April 24, 2020 (HealthDay News) — Anesthesiologists on the front lines of treating surgical COVID-19 patients in Turkey are generally knowledgeable about airway management, according to the results of a national survey published online April 6 in Surgical Infections.

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COVID-19 Outcomes Worse With Diabetes, Hyperglycemia

FRIDAY, April 24, 2020 (HealthDay News) — Diabetes and/or uncontrolled hyperglycemia occur frequently among hospitalized patients with COVID-19 and are associated with worse outcomes, according to a study accepted for publication in the Journal of Diabetes Science and Technology.

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SARS-CoV-2 Can Spread Rapidly in Homeless Shelters

THURSDAY, April 23, 2020 (HealthDay News) — Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can spread rapidly in homeless shelters, according to two studies published in the April 22 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text – Tobolowsky
Abstract/Full Text – Mosites

‘Health Force’ to Combat Pandemic Proposed by U.S. Senators

THURSDAY, April 23, 2020 (HealthDay News) — A bill to create a “Health Force” to help combat the U.S. COVID-19 outbreak has been announced by two Democratic senators.

NBC News Article

White House Announces Payment Plan for Uninsured COVID-19 Patients

THURSDAY, April 23, 2020 (HealthDay News) — A plan to begin paying hospitals and doctors who treat uninsured COVID-19 patients was announced by U.S. Health and Human Services Secretary Alex Azar on Wednesday.

AP News Article

ACEIs/ARBs Not Linked to Severity or Mortality of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) — For patients with hypertension hospitalized with COVID-19 infections, angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) are not associated with the severity or mortality of COVID-19, according to a brief report published online April 23 in JAMA Cardiology.

Abstract/Full Text

Mild, No Symptoms Seen for Most Children With SARS-CoV-2 Infection

THURSDAY, April 23, 2020 (HealthDay News) — Most children with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have mild respiratory symptoms or are asymptomatic, according to a review published online April 22 in JAMA Pediatrics.

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Chronic Conditions, Obesity Common in Fatal Cases of EVALI

THURSDAY, April 23, 2020 (HealthDay News) — Chronic conditions, including asthma, mental health conditions, and obesity, are common among fatal cases of e-cigarette, or vaping, product use-associated lung injury (EVALI), according to a study published in the April 23 issue of the New England Journal of Medicine.

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Editorial

AAD Establishes Registry for Skin Manifestations of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) — A registry has been created for reporting skin manifestations of COVID-19 following reports of patients presenting with skin conditions, including findings outlined in a letter to the editor published online March 26 in the Journal of the European Academy of Dermatology and Venereology.

Registry
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Lopinavir/Ritonavir, Umifenovir Ineffective for Mild COVID-19

THURSDAY, April 23, 2020 (HealthDay News) — For patients hospitalized with mild/moderate COVID-19, lopinavir/ritonavir (LPV/r) or umifenovir (Arbidol) monotherapy offers little benefit, according to a study published online April 17 in Med.

Abstract/Full Text

Hydroxychloroquine Seems Not to Cut Ventilator Use in COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) — There is no evidence that use of hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) reduces the risks for mechanical ventilation or death from any cause in patients hospitalized with COVID-19, according to a study that has not yet been peer reviewed and was posted online April 21 at medRxiv.org.

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Expert Panel: There Are No Proven Drug Treatments for COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) — There is no proven drug treatment for COVID-19 patients, according to a panel of experts convened by the U.S. National Institute of Allergy and Infectious Diseases.

The New York Times Article

Rapid COVID-19 Test Can Produce False Negatives

WEDNESDAY, April 22, 2020 (HealthDay News) — A widely used rapid COVID-19 test can produce false negatives if a certain solution is used to move or store patients’ samples, the test’s maker said.

CNN Article

ST-Segment Elevation Described in Patients With COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) — For patients with COVID-19 who have ST-segment elevation, indicating potential acute myocardial infarction, there is considerable variability in presentation, and prognosis is poor, according to a letter to the editor published online April 17 in the New England Journal of Medicine.

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Living Alone Ups Admission Risk for Respiratory Disease in Seniors

WEDNESDAY, April 22, 2020 (HealthDay News) — For older adults, the risk for hospital admission due to respiratory disease (RD) is increased in association with living alone and social disengagement, according to a study published online April 21 in Thorax.

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Obesity Ups Risk for COVID-19 Severity

WEDNESDAY, April 22, 2020 (HealthDay News) — There is a high frequency of obesity among patients admitted to intensive care for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a study published online April 9 in Obesity.

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Scoring System Helps Guide Surgical Care During COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) — A scoring system for medically necessary time-sensitive (MeNTS) procedures can facilitate decision making and triage in the setting of COVID-19, according to a study published online April 9 in the Journal of the American College of Surgeons.

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LA County COVID-19 Infections Far Exceed Number of Confirmed Cases

TUESDAY, April 21, 2020 (HealthDay News) — An early analysis of antibody testing from Los Angeles County reveals a COVID-19 infection rate that is up to 55 times the number of confirmed COVID-19 cases.

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FDA Authorizes COVID-19 Test That Uses Samples Collected at Home

TUESDAY, April 21, 2020 (HealthDay News) — The U.S. Food and Drug Administration has approved emergency use of the first COVID-19 test that enables patients to take samples at home.

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176,190 U.S. Children Estimated to Have SARS-CoV-2 by April 6, 2020

TUESDAY, April 21, 2020 (HealthDay News) — About 176,190 children nationwide were estimated to be infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by April 6, 2020, according to a study published online April 16 in the Journal of Public Health Management & Practice.

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Most Older Adults With New Dementia Die Within Five Years

TUESDAY, April 21, 2020 (HealthDay News) — Most community-dwelling older adults with newly identified dementia die or are admitted to a long-term care home within five years, according to a study published online April 20 in CMAJ, the journal of the Canadian Medical Association.

Abstract/Full Text

Expanding Symptom Screening Criteria Can Up COVID-19 Detection

TUESDAY, April 21, 2020 (HealthDay News) — Expanding COVID-19 symptom screening criteria to include myalgias and chills could identify more health care personnel (HCP) with the illness, according to a research letter published online April 17 in the Journal of the American Medical Association.

Abstract/Full Text

Coinfection With SARS-CoV-2, Other Respiratory Pathogens ID’d

TUESDAY, April 21, 2020 (HealthDay News) — About 20 percent of specimens positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are positive for other respiratory pathogens, according to a research letter published online April 15 in the Journal of the American Medical Association.

Abstract/Full Text

Cardiac Cath Lab STEMI Activations Drop During Pandemic

TUESDAY, April 21, 2020 (HealthDay News) — During the COVID-19 pandemic, there has been a 38 percent reduction in U.S. cardiac catheterization laboratory ST-segment elevation myocardial infarction (STEMI) activations, according to a research letter published online April 10 in the Journal of the American College of Cariology.

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Reduced Power Plant Emissions Tied to Better Asthma Measures

MONDAY, April 20, 2020 (HealthDay News) — Retirement of coal-fired power plants or installation of stricter emissions controls is associated with better asthma-related outcomes, according to a study published online April 13 in Nature Energy.

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Lab Protocol Failures Led to Ineffective COVID-19 Tests From CDC

MONDAY, April 20, 2020 (HealthDay News) — The first COVID-19 tests in the United States were ineffective due to poor laboratory practices at the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration said.

The New York Times Article

Public Health Measures Cut COVID-19 Transmission in Hong Kong

MONDAY, April 20, 2020 (HealthDay News) — Public health measures implemented to suppress local transmission of COVID-19 in Hong Kong were associated with reduced transmission of COVID-19 and influenza, according to a study published online April 17 in The Lancet Public Health.

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Diabetes Increases Risk for Poorer Prognosis in COVID-19

MONDAY, April 20, 2020 (HealthDay News) — Diabetes may contribute to more severe symptoms, rapid progression, and poorer prognosis in patients infected with COVID-19, according to a study published online March 31 in Diabetes Metabolism Research and Reviews.

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Benefit of Social Distancing Outweighs Economic Impact

MONDAY, April 20, 2020 (HealthDay News) — The economic benefits of lives saved through social distancing substantially outweigh the value of the projected losses to the U.S. economy, according to a study to be published in a forthcoming issue of the Journal of Benefit-Cost Analysis.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 13 to 17, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Insomnia Common Among Medical Staff During COVID-19 in China

FRIDAY, April 17, 2020 (HealthDay News) — More than one-third of medical staff members in hospitals during the coronavirus disease 2019 (COVID-19) outbreak in China reported insomnia symptoms, according to a study published online April 14 in Frontiers in Psychiatry.

Abstract/Full Text

Incidence of SARS-CoV-2 Infection Stable in Iceland

FRIDAY, April 17, 2020 (HealthDay News) — In Iceland, the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was stable through 20 days of screening, according to a study published online April 14 in the New England Journal of Medicine.

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Asthma Not Common in COVID-19 Patients Who Have Died

FRIDAY, April 17, 2020 (HealthDay News) — Asthma is not among the top 10 chronic health problems in people who have died from coronavirus disease 2019 (COVID-19) in New York state, even though many health experts have warned that people with asthma are at increased risk for severe illness if they get COVID-19.

The New York Times Article

Scientists Design Protective Respirator for Health Care Workers

THURSDAY, April 16, 2020 (HealthDay News) — With protective gear in short supply, Duke University researchers say they have designed a much-needed respirator for health care workers battling coronavirus disease 2019 (COVID-19).

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IDSA Issues Rapid Guidelines for Treatment of COVID-19

FRIDAY, April 17, 2020 (HealthDay News) — In rapid guidelines issued by the Infectious Diseases Society of America (IDSA), recommendations are presented for the treatment and management of coronavirus disease 2019 (COVID-19).

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Chest X-Ray Findings Normal for Many Confirmed COVID-19 Cases

FRIDAY, April 17, 2020 (HealthDay News) — Most patients presenting to urgent care centers with confirmed coronavirus disease 2019 (COVID-19) have normal or mildly abnormal findings on chest X-rays (CXRs), according to a study published online April 14 in the Journal of Urgent Care Medicine.

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Removal of Flavored E-Cigarette Products Likely Ineffective

FRIDAY, April 17, 2020 (HealthDay News) — Juul sales recovered within weeks following a dip after the company withdrew some flavored products from stores, even surpassing sales before the withdraw, according to a study published online April 16 in the American Journal of Public Health.

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Risk for Severe COVID-19 May Be Up in People With COPD, Smokers

FRIDAY, April 17, 2020 (HealthDay News) — Active cigarette smokers and individuals with chronic obstructive pulmonary disease (COPD) have up-regulation of angiotensin converting enzyme II (ACE-2) expression in the lower airways, which could explain the increased risk for severe COVID-19 in these subpopulations, according to a study published online April 8 in the European Respiratory Journal.

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Recurrent Winter Outbreaks of SARS-CoV-2 Projected

THURSDAY, April 16, 2020 (HealthDay News) — Recurrent winter outbreaks of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are projected to occur after the initial pandemic wave, according to a study published online April 14 in Science.

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Sharp Drop in Demand Seen for COVID-19 Tests at Private Labs

THURSDAY, April 16, 2020 (HealthDay News) — There has been such a drop in demand for coronavirus disease 2019 (COVID-19) tests at private labs in the United States that they have “considerable” unused capacity and can test more patients with less severe symptoms, the American Clinical Laboratory Association (ACLA) says.

NBC News Article

FDA Urges COVID-19 Survivors to Donate Plasma

THURSDAY, April 16, 2020 (HealthDay News) — The U.S. Food and Drug Administration is asking Americans who have recovered from coronavirus disease 2019 (COVID-19) to donate their blood plasma to help fight the pandemic.

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CRISPR-Based Test Can Diagnose COVID-19 in Under 60 Minutes

THURSDAY, April 16, 2020 (HealthDay News) — Researchers say they have developed a low-cost swab test that can diagnose coronavirus disease 2019 (COVID-19) infections in about 45 minutes.

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Telehealth Usage Was Growing Among Internists Prior to COVID-19

THURSDAY, April 16, 2020 (HealthDay News) — There is wide variation in the use of telehealth among internal medicine physicians and subspecialists, according the “2020 American College of Physicians (ACP) Member Survey About Telehealth Implementation.”

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Heavy Wildfire Smoke Tied to Higher Risk for Cardiac Arrest

WEDNESDAY, April 15, 2020 (HealthDay News) — Risk for out-of-hospital cardiac arrest increases by 70 percent with exposure to heavy wildfire smoke, according to a study published online April 15 in the Journal of the American Heart Association.

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Compliance With Self-Isolation Influenced by Compensation

WEDNESDAY, April 15, 2020 (HealthDay News) — In the era of coronavirus disease 2019 (COVID-19), compliance with self-isolation is influenced by compensation, with very high compliance seen when compensation for lost wages is assured, according to a report published online April 9 in Health Affairs.

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Obesity Is Risk Factor for COVID-19 Hospital Admission in <60s

WEDNESDAY, April 15, 2020 (HealthDay News) — Obesity is associated with admission to the hospital for coronavirus disease 2019 (COVID-19) patients, according to a study published online April 9 in Clinical Infectious Diseases and a study not yet peer reviewed and posted on medRxiv.org.

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Survey Shows Lack of COVID-19 Concern Even Among Those at Risk

WEDNESDAY, April 15, 2020 (HealthDay News) — Many individuals at greater risk for coronavirus disease 2019 (COVID-19) complications did not believe the virus would affect them at the beginning of Chicago’s outbreak, according to a study published online April 9 in the Annals of Internal Medicine.

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SARS-CoV-2 Contamination of Air, Surfaces Examined in ICU, Wards

WEDNESDAY, April 15, 2020 (HealthDay News) — Considerable severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) contamination of air and object surfaces is reported in intensive care units (ICUs) and general coronavirus disease 2019 (COVID-19) wards (GW), according to a study published online April 10 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

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Public Health Interventions Improved COVID-19 Control in Wuhan

WEDNESDAY, April 15, 2020 (HealthDay News) — Multifaceted public health interventions improved control of the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, according to a study published online April 10 in the Journal of the American Medical Association.

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Common Coronaviruses Are Highly Seasonal

WEDNESDAY, April 15, 2020 (HealthDay News) — Common coronaviruses circulate seasonally, according to a study published online April 4 in the Journal of Infectious Diseases.

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Intubation Initiated in One in Five Who Died of COVID-19 in China

WEDNESDAY, April 15, 2020 (HealthDay News) — Many patients who died from coronavirus disease 2019 (COVID-19) in China may have had delayed intubation, according to a research letter published online April 10 in JAMA Network Open.

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Smell, Taste Impairment Linked to COVID-19 Positivity

TUESDAY, April 14, 2020 (HealthDay News) — Smell and taste impairment are strongly associated with coronavirus disease 2019 (COVID-19) positivity, according to a study published online April 12 in the International Forum of Allergy & Rhinology.

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Review: Quarantine Effective for Reducing Infection, Death

TUESDAY, April 14, 2020 (HealthDay News) — Quarantine is effective for reducing the number of people infected and deaths from coronavirus disease 2019 (COVID-19), according to a review published online April 8 in the Cochrane Database of Systematic Reviews.

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CDC: Public Policy Measures Important for Social Distancing

TUESDAY, April 14, 2020 (HealthDay News) — Community mobility in four metropolitan areas decreased with the introduction of public policy measures supporting social distancing, which could help slow the spread of coronavirus disease 2019 (COVID-19), according to research published in the April 13 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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U.S. Government Says COVID-19 Antibody Tests Must Be Free

TUESDAY, April 14, 2020 (HealthDay News) — Health insurers and Medicaid must provide free coverage for tests to detect coronavirus 2019 (COVID-19) antibodies in people who have been infected, the federal government says.

CBS News Article
Johns Hopkins University

First Saliva Test for COVID-19 Approved by FDA

TUESDAY, April 14, 2020 (HealthDay News) — The first saliva test for coronavirus 2019 (COVID-19) was approved Monday by the U.S. Food and Drug Administration.

AP News Article
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Medical Masks May Be Sufficient During COVID-19 Routine Care

TUESDAY, April 14, 2020 (HealthDay News) — Use of medical masks, such as surgical or procedural masks, does not increase the risk for viral infection or respiratory illness, and their use may serve as a protective measure in instances of N95 respirator shortages, according to the results of a meta-analysis published online April 4 in Influenza and Other Respiratory Viruses.

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COVID-19 RNA Detectable in Patient Fecal Matter

TUESDAY, April 14, 2020 (HealthDay News) — The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is detectable in the feces of COVID-19 patients and remains even after negative conversion in pharyngeal swabs, according to a study published online April 3 in the Journal of Medical Virology.

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First Wave of COVID-19 Abated With Control Measures in China

TUESDAY, April 14, 2020 (HealthDay News) — Interventions implemented in China interrupted coronavirus disease 2019 (COVID-19) transmission in all areas outside of Hubei, and low transmissibility can be maintained by monitoring the instantaneous effective reproduction number (Rt), according to a study published online April 8 in The Lancet.

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Model Forecasts When COVID-19 Demand Will Exceed Capacity

TUESDAY, April 14, 2020 (HealthDay News) — The COVID-19 Hospital Impact Model (CHIME), a publicly available tool, can help hospitals predict the timing of saturated capacity, according to a report published online April 7 in the Annals of Internal Medicine.

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Physicians Report Expanding Use of Off-Label COVID-19 Treatments

MONDAY, April 13, 2020 (HealthDay News) — Hydroxychloroquine usage is expanding globally to treat coronavirus 2019 (COVID-19), although plasma from recovered patients is perceived as more effective than hydroxychloroquine, according to a report released by Sermo.

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Survey IDs Those Most Affected by One-Month COVID-19 Lockdown

MONDAY, April 13, 2020 (HealthDay News) — Adults who stopped working during coronavirus 2019 (COVID-19)-related lockdowns in China report worse mental and physical health, according to a study published online April 4 in Psychiatry Research.

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COVID-19 Antibody Tests Underway in California

MONDAY, April 13, 2020 (HealthDay News) — Large-scale studies of tests to check for antibodies to coronavirus 2019 (COVID-19) are underway in California. The findings from this research could help the United States develop strategies to get people back to work and restart the economy.

NBC News Article

Chloroquine COVID-19 Trial Stopped After Patient Deaths

MONDAY, April 13, 2020 (HealthDay News) — A study of chloroquine in coronavirus 2019 (COVID-19) patients was halted due to potentially deadly side effects.

The New York Times Article

High Rates of Appropriate E-Consults Seen Across Specialties

MONDAY, April 13, 2020 (HealthDay News) — The rates of appropriate electronic consultations (e-consults) are high across specialties, according to a study published online April 14 in the Annals of Internal Medicine.

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CDC Report Details Geographic Variation in U.S. COVID-19 Cases, Deaths

MONDAY, April 13, 2020 (HealthDay News) — There is variation in the cumulative incidence of coronavirus disease 2019 (COVID-19) across jurisdictions in the United States, according to research published in the April 10 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Remdesivir May Improve Oxygen-Support Class in Severe COVID-19

MONDAY, April 13, 2020 (HealthDay News) — Improvement in oxygen support status was observed in 68 percent of patients hospitalized with severe coronavirus disease 2019 (COVID-19) who received compassionate use of remdesivir, according to a study published online April 10 in the New England Journal of Medicine.

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Recommendations Issued for Use of Imaging in Adults With COVID-19

MONDAY, April 13, 2020 (HealthDay News) — In a multinational consensus statement from the Fleischner Society, published online April 7 in Radiology, recommendations are presented for use of imaging in patients with coronavirus disease 2019 (COVID-19).

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Mechanical Ventilation Needed by Most COVID-19 Patients in ICU

MONDAY, April 13, 2020 (HealthDay News) — Most patients with coronavirus disease 2019 (COVID-19) requiring treatment in an intensive care unit (ICU) require mechanical ventilation, according to a study published online April 6 in the Journal of the American Medical Association.

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Guidance Issued for Infants Born to Mothers With COVID-19

MONDAY, April 13, 2020 (HealthDay News) — In an initial guidance document issued by the American Academy of Pediatrics, recommendations are presented for the management of infants born to mothers with suspected or confirmed coronavirus disease 2019 (COVID-19).

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 6 to 10, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Contact Tracing ID’d Large Multifamily COVID-19 Cluster in Chicago

FRIDAY, April 10, 2020 (HealthDay News) — One index patient with COVID-19 and only mild symptoms attended two family gatherings and likely triggered a chain of transmission that included 15 other confirmed and probable cases with three deaths, according to research published in the April 8 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Neurologic Effects Seen in a Third of Hospitalized COVID-19 Patients

FRIDAY, April 10, 2020 (HealthDay News) — Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.

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Temperature, UV Radiation Not Linked to Incidence of COVID-19

FRIDAY, April 10, 2020 (HealthDay News) — Ambient temperature and ultraviolet (UV) radiation are not associated with the cumulative incidence rate or basic reproduction number (R0) of coronavirus disease 2019 (COVID-19), according to a research letter published online April 8 in the European Respiratory Journal.

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FDA Approves New Way to Decontaminate N95 Face Masks

FRIDAY, April 10, 2020 (HealthDay News) — The second emergency use authorization to decontaminate N95 face masks and equivalents for reuse by hospital health care workers has been issued by the U.S. Food and Drug Administration.

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Anxiety Up for Nonmedical Health Care Workers Versus Those on Front Lines

FRIDAY, April 10, 2020 (HealthDay News) — Non-medically trained health care workers caring for patients with coronavirus disease 2019 (COVID-19) have an increased prevalence of anxiety compared with medically trained health care workers, according to a research letter published online April 6 in the Annals of Internal Medicine.

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Face Masks Offer Slight Protective Effect From Flu-Like Illness

FRIDAY, April 10, 2020 (HealthDay News) — Wearing face masks could be slightly protective against primary infection with influenza-like illness from casual community contact, according to a review that has not yet been peer reviewed and was posted online April 6 at medRxiv.org.

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Current Models for COVID-19 Diagnosis, Prognosis Unreliable

FRIDAY, April 10, 2020 (HealthDay News) — Novel coronavirus (COVID-19)-related models that are published in the literature are poorly reported and at high risk for bias, raising concern that their predictions could be unreliable when applied in daily practice, according to a review published online April 7 in The BMJ.

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Doctors Report on Four COVID-19 Infections in Newborns in China

FRIDAY, April 10, 2020 (HealthDay News) — Compared with adults, symptoms of COVID-19 in newborn babies are milder and outcomes are less severe, according to a research letter published online April 8 in the European Respiratory Journal.

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Adult Smoking, Cessation Tied to Smoking Intensity in Adolescence

FRIDAY, April 10, 2020 (HealthDay News) — The prevalence rates of smoking and cessation in adulthood are associated with levels of childhood smoking intensity, according to a study published in the April 9 issue of the Journal of the American Heart Association.

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Clinical Trial Underway to Test Nitric Oxide in COVID-19 Patients

THURSDAY, April 9, 2020 (HealthDay News) — Doctors at the University of Alabama at Birmingham (UAB) are enrolling patients in an international clinical trial to find out if inhaled nitric oxide benefits those with novel coronavirus (COVID-19) who have severely damaged lungs.

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Another COVID-19 Vaccine Trial Begins in the United States

THURSDAY, April 9, 2020 (HealthDay News) — Another clinical trial of an experimental vaccine for the novel coronavirus 2019 (COVID-19) has been launched by U.S. researchers.

AP News Article

FDA Warns of False Claims That Chlorine Dioxide Can Treat COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — A warning letter has been sent to a company marketing fraudulent and dangerous chlorine dioxide products for the prevention and treatment of the novel coronavirus (COVID-19), the U.S. Food and Drug Administration says.

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COVID-19 Came to New York City From Europe, Not Asia

THURSDAY, April 9, 2020 (HealthDay News) — The novel coronavirus (COVID-19) has been circulating in New York City for longer than previously believed and most cases can be traced back to Europe, new research reveals.

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NIH Launches Clinical Trial of Hydroxychloroquine for COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — A clinical trial to assess the antimalarial drug hydroxychloroquine as a treatment for adults with the novel coronavirus (COVID-19) is now underway, the U.S. National Institutes of Health said Thursday.

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Racial Differences Seen for Cancer Diagnosis, Treatment, Survival

THURSDAY, April 9, 2020 (HealthDay News) — Stage at diagnosis, treatment, and survival differ by race and ethnicity for patients with one of the nine leading cancers, according to a study published online April 8 in JAMA Network Open.

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Older Adults, Men, Preexisting Conditions Tied to COVID-19 Death

THURSDAY, April 9, 2020 (HealthDay News) — Researchers have identified the most common clinical characteristics among 109 patients out of 1,017 with confirmed novel coronavirus (COVID-19) pneumonia who died of COVID-19-related pneumonia in Wuhan, China; their findings were published online April 7 in the Annals of the American Thoracic Society.

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Convalescent Plasma Treatment Promising in Severe COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — One dose of convalescent plasma (CP) therapy is well tolerated and can potentially improve clinical symptoms in severe cases with coronavirus disease 2019 (COVID-19), according to a study published online April 6 in the Proceedings of the National Academy of Sciences.

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ATS Provides Interim Guidance for Management of COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — In a guidance document issued by the American Thoracic Society, interim recommendations are presented for management of coronavirus disease 2019 (COVID-19).

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HHS Report Looks at Hospital Experiences With COVID-19

THURSDAY, April 9, 2020 (HealthDay News) — A report issued by the U.S. Department of Health and Human Services Office of Inspector General provides a national snapshot of hospital experiences in response to the coronavirus disease 2019 (COVID-19).

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Children With COVID-19 Do Not Always Have Cough, Fever

WEDNESDAY, April 8, 2020 (HealthDay News) — Children with coronavirus disease 2019 (COVID-19) have symptoms of fever, cough, or shortness of breath less often than adults with the disease, according to research published in the April 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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CDC Removes Prescribing Guidelines for Antimalarial Drugs

WEDNESDAY, April 8, 2020 (HealthDay News) — Guidelines for doctors on how to prescribe two antimalarial drugs that some believe may treat the novel coronavirus (COVID-19) are no longer available on the U.S. Centers for Disease Control and Prevention website.

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COVID-19 Killing Two Times More Men Than Women in NYC

WEDNESDAY, April 8, 2020 (HealthDay News) — The novel coronavirus (COVID-19) death rate in New York City is two times higher among men than among women, and men also have higher rates of infection and hospitalization, new data show.

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Surgical, Cotton Masks Not Effective for Filtering SARS-CoV-2

WEDNESDAY, April 8, 2020 (HealthDay News) — For patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), neither surgical nor cotton masks effectively filter SARS-CoV-2 during coughs, according to a research letter published online April 6 in the Annals of Internal Medicine.

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Celiac Disease May Slightly Increase Mortality Risk

WEDNESDAY, April 8, 2020 (HealthDay News) — Patients with celiac disease have a small but statistically significantly increased mortality risk compared with controls, according to a study published in the April 7 issue of the Journal of the American Medical Association.

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Guidelines Developed for COVID-19 Patients in ICU

WEDNESDAY, April 8, 2020 (HealthDay News) — In guidelines issued by the international Surviving Sepsis Campaign initiative, published in Critical Care Medicine and Intensive Care Medicine, recommendations are presented for the management of novel coronavirus disease 2019 (COVID-19) patients in the intensive care unit (ICU).

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Children Have Milder Disease Course, Better COVID-19 Prognosis

WEDNESDAY, April 8, 2020 (HealthDay News) — Children diagnosed with COVID-19 have a milder disease course and better prognoses than adults, according to a review published online March 23 in Acta Paediatrica.

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Compliance Higher if Stay-at-Home Extensions Are Shorter Than Thought

TUESDAY, April 7, 2020 (HealthDay News) — When hypothetical stay-at-home orders in response to COVID-19 are extended longer than expected, people become less willing to increase self-isolation efforts, according to a working paper released by the National Bureau of Economic Research.

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Serious Concerns Associated With COVID-19 Pandemic Reported

TUESDAY, April 7, 2020 (HealthDay News) — Serious concerns are associated with coronavirus disease 2019 (COVID-19), and many individuals are preparing by washing hands and self-isolating, according to a research letter published online April 7 in JAMA Internal Medicine.

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Side Effects Seen With Use of Chloroquine Against COVID-19

TUESDAY, April 7, 2020 (HealthDay News) — The use of the antimalarial drug chloroquine to treat COVID-19 patients has been halted at several Swedish hospitals due to reported side effects such as cramps and loss of peripheral vision. Sahlgrenska University Hospital is one of those facilities. It stopped the use of chloroquine in the treatment of COVID-19 about two weeks ago.

Newsweek Article
Johns Hopkins University

Most COVID-19 Fatalities Are Men Over 50 With Chronic Disease

TUESDAY, April 7, 2020 (HealthDay News) — Most fatal cases of coronavirus disease 2019 (COVID-19) occur in men aged older than 50 years with noncommunicable chronic diseases, according to a study published online April 3 in the American Journal of Respiratory and Critical Care Medicine.

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School Closures Could Further Complicate COVID-19 Effort

TUESDAY, April 7, 2020 (HealthDay News) — Potential contagion prevention from school closures needs to be weighed against the potential loss of health care workers due to child care obligations during the coronavirus disease 2019 (COVID-19) pandemic, according to a study published online April 3 in The Lancet Public Health.

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‘Mod’ E-Cigarette Users Smoke More Cigarettes One Year Later

TUESDAY, April 7, 2020 (HealthDay News) — Baseline modifiable (mod) electronic cigarette device users smoke more cigarettes at one-year follow-up than vape pen users, according to a study published online April 6 in Pediatrics.

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FDA Authorizes Use of Chinese-Approved Masks in United States

MONDAY, April 6, 2020 (HealthDay News) — Emergency use authorization of protective masks that do not meet American standards has been announced by the U.S. Food and Drug Administration.

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Social Distancing Minimizes COVID-19 Spread in Assisted Living

MONDAY, April 6, 2020 (HealthDay News) — Early implementation of social distancing and preventive measures after identification of coronavirus disease 2019 (COVID-19) can minimize virus spread in senior independent and assisted living communities, according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Majority of Physicians Report Serious Concerns About COVID-19

MONDAY, April 6, 2020 (HealthDay News) — According to a national survey conducted by Harvard Medical School, the RAND Corporation, and Doximity, practicing physicians currently report substantial concerns about supplies, the government response, and availability of testing amid the COVID-19 pandemic.

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Sentinel Surveillance Can Help Monitor Epidemiology of COVID-19

MONDAY, April 6, 2020 (HealthDay News) — Rapid sentinel surveillance can help monitor the epidemiology of coronavirus disease 2019 (COVID-19), according to research published in the April 3 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Comorbidity, Age, Time to Treatment Linked to COVID-19 Progression

MONDAY, April 6, 2020 (HealthDay News) — Factors associated with coronavirus disease 2019 (COVID-19) progression include comorbidity, age, and time from illness onset to antiviral treatment, according to a study published online March 27 in the Journal of Internal Medicine.

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Extracorporeal Membrane Oxygenation Might Aid in Severe COVID-19

MONDAY, April 6, 2020 (HealthDay News) — Extracorporeal membrane oxygenation (ECMO) support might improve clinical outcomes in severe cases of coronavirus disease 2019 (COVID-19) that cannot be adequately managed with mechanical ventilation alone, according to research published online March 30 in the ASAIO Journal.

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Hydroxychloroquine Can Shorten Time to Recovery in COVID-19

MONDAY, April 6, 2020 (HealthDay News) — Hydroxychloroquine (HCQ) can shorten time to clinical recovery and promote pneumonia absorption among patients with coronavirus disease 2019 (COVID-19), according to a study that has not yet been peer reviewed and was posted online March 31 at medRxiv.org.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 30 to April 3, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Enrollment Begins in NIH-Sponsored Trial of Remdesivir for COVID-19 Patients

FRIDAY, April 3, 2020 (HealthDay News) — A number of institutions this week announced their participation in an international clinical drug trial evaluating the safety and efficacy of remdesivir in hospitalized patients with the novel coronavirus 2019 (COVID-19).

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Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice

FRIDAY, April 3, 2020 (HealthDay News) — Microneedle array (MNA) delivery of trimeric coronavirus spike (S) protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to research published online April 2 in EBioMedicine.

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Presymptomatic Transmission of SARS-CoV-2 ID’d in Singapore

FRIDAY, April 3, 2020 (HealthDay News) — Presymptomatic transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been observed in epidemiological clusters in Singapore, with transmission occurring one to three days before symptom onset, according to research published in the April 1 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Model Projects COVID-19 Deaths in Italy Through Mid-April

FRIDAY, April 3, 2020 (HealthDay News) — Modeling suggests that in Italy, the number of coronavirus disease 2019 (COVID-19) intensive care unit (ICU) patients will continue increasing into April, according to a report published April 1 by the European Society of Anaesthesiology.

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Rivaroxaban Prevents VTE After Lower-Limb Surgery

FRIDAY, April 3, 2020 (HealthDay News) — Following nonmajor orthopedic surgery of the lower limb, rivaroxaban is superior to enoxaparin for prevention of major venous thromboembolism, according to a study published online March 29 in the New England Journal of Medicine.

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COPD Independent Risk Factor for Lung Cancer

FRIDAY, April 3, 2020 (HealthDay News) — Chronic obstructive pulmonary disease (COPD) is an independent risk factor for lung cancer incidence, regardless of smoking status, according to a study published online April 2 in Thorax.

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Amid COVID-19 Crisis, Blood Donor Restrictions Eased

FRIDAY, April 3, 2020 (HealthDay News) — America is in urgent need of blood donations during the COVID-19 pandemic, so the U.S. Food and Drug Administration said Thursday it will relax donor restrictions placed on gay and bisexual men and others.

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Gastrointestinal Symptoms Common in COVID-19 Patients

FRIDAY, April 3, 2020 (HealthDay News) — Gastrointestinal symptoms are common in patients with coronavirus disease 2019 (COVID-19), with increased prevalence seen in the later stages of the epidemic in China, according to a review published online March 29 in Alimentary Pharmacology & Therapeutics.

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N.Y. Hospital Converts Sleep Apnea Machines Into Ventilators

FRIDAY, April 3, 2020 (HealthDay News) — As COVID-19 pushes American hospitals to the breaking point, intensive care units are finding creative ways to deal with a looming shortage of lifesaving mechanical ventilators.

Northwell Health Press Release
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Test for COVID-19 Antibodies Approved by FDA

FRIDAY, April 3, 2020 (HealthDay News) — The first COVID-19 virus antibody test for use in the United States has been approved by the Food and Drug Administration.

The New York Times Article
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Johns Hopkins University

Unemployed Workers Less Likely to Be Uninsured Post-ACA

THURSDAY, April 2, 2020 (HealthDay News) — Following implementation of the Affordable Care Act (ACA), unemployed workers were less likely to be uninsured, and uninsurance rates decreased more in states with Medicaid expansion, according to a report from the Urban Institute and the Robert Wood Johnson Foundation.

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35.1 Percent of Workers Report Work-Related Health Problems

THURSDAY, April 2, 2020 (HealthDay News) — More than one-third of employed individuals report work-related health problems, according to research published in the April 3 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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COVID-19 Outbreak Described in Long-Term Care Facility

THURSDAY, April 2, 2020 (HealthDay News) — Outbreaks of coronavirus disease 2019 (COVID-19) can have a considerable impact on long-term care facilities, according to a report published online March 27 in the New England Journal of Medicine.

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CT Scores Higher With Longer Time to COVID-19 Diagnosis

THURSDAY, April 2, 2020 (HealthDay News) — Patients with coronavirus disease 2019 (COVID-19) with longer time from symptom onset to diagnosis have higher computed tomography (CT) scores and longer time to disease resolution, according to a study published online March 30 in the American Journal of Roentgenology.

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Transmission Control Measures Tied to Delay in COVID-19 Growth

THURSDAY, April 2, 2020 (HealthDay News) — Transmission control measures implemented in Wuhan were associated with a delay in epidemic growth during the first 50 days of the coronavirus disease 2019 (COVID-19) epidemic in China, according to a study published online March 31 in Science.

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Severe COVID-19 Risk Up With Existing Health Conditions in U.S.

WEDNESDAY, April 1, 2020 (HealthDay News) — In the United States, individuals with underlying health conditions have an increased risk for severe coronavirus disease 2019 (COVID-19), according to research published in the March 31 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Imported Masks, Other Medical Supplies Arriving in U.S.

WEDNESDAY, April 1, 2020 (HealthDay News) — For the first time since February, imported N95 medical masks are arriving in the United States, but they are not nearly enough to meet demand as COVID-19 cases climb.

AP News Article
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Half of People With COVID-19 Do Not Have Symptoms, Iceland Testing Shows

WEDNESDAY, April 1, 2020 (HealthDay News) — Up to half of people who test positive for the new coronavirus do not have symptoms, results from Iceland show.

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Persistent Positive SARS-CoV-2 Found in Sputum, Feces Samples

WEDNESDAY, April 1, 2020 (HealthDay News) — Some patients with coronavirus disease 2019 (COVID-19) remain positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in sputum or feces after pharyngeal samples become negative, according to a research letter published online March 30 in the Annals of Internal Medicine.

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U.S. Coronavirus Death Toll Could Reach 240,000, Task Force Warns

WEDNESDAY, April 1, 2020 (HealthDay News) — The White House coronavirus task force delivered a tough statistic to Americans late Tuesday, warning that the U.S. death toll from COVID-19 could climb to 240,000, even with social distancing policies in place.

CBS News Article
Johns Hopkins University
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