Antidepressant drugs are beneficial interesting non-psychiatric and psychiatric illnesses including disorders in the spinal cord. In some cases, spine surgeons are not familiar with the advantages and disadvantages of these drugs as a part of the medical treatment for the diseases of the spine. The study has a purpose to identify the benefits and the risks of antidepressant drugs in spine surgery based on around 17 published articles from 2000 to 2018. The studies say that these drugs can be more effective for the patient who goes under depression due to spinal cord injury. Patients become depressed for several reasons like higher cost, prolonged hospital stay, controversial reports regarding spinal cord injury, and many more. The anti-depression drugs help the patient to have satisfaction and live a quality life after the surgery. It also reduces the pain and risk of delirium in postoperative situations. Even before the surgery, the patients might have psychiatric problems due to anxiety and depression for the spinal cord injury. The antidepressant drugs can pull up the patients from that situation so that the surgeons can perform the surgery properly. 

Therefore, the study has come to the conclusion that antidepressant drugs have greater advantages in spinal surgery for patients. It also helps spine surgeons to understand the benefits and risks of these drugs for spinal surgery. That will optimize the outcomes and avoid the potential hazards in spinal surgery.