The study aimed to establish whether a mother’s PCOS symptoms can predict her daughter’s future PCOS clinical profile.

This was a cross-sectional study of 57 adolescents who attended a pediatric gynecology clinic between 2017 and 2019 and had an established PCOS diagnosis according to the 2018 criteria of the European Society of Human Reproduction and Embryology. A clinical examination and pelvic ultrasound were performed, and the level of total testosterone was measured. The girls’ mothers completed a structured questionnaire concerning PCOS symptoms.

The znalysis reported that 40% of mothers had experienced menstrual irregularities, 50% hirsutism, 67% acne, and 12% had a confirmed PCOS diagnosis.

Our study population had several markers of poor metabolic health passed down from mother to daughter. No direct link was found between a mother’s PCOS symptoms and those of her adolescent daughter. A more comprehensive study should be conducted using a more extensive study sample to establish definitive links between a mother’s symptoms and those of her daughter. Additionally, a follow-up assessment of our studied adolescents would be appropriate to evaluate their symptoms’ progress.