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Allergy & Immunology General

Pregnancy With Allergen-Specific Immunotherapy: Risk of Congenital Malformations & Other Negative Pregnancy Outcomes

Jun 17, 2022

For a study, the researchers sought to assess the safety of allergen-specific immunotherapy (AIT) during pregnancy, particularly the risk of congenital abnormalities. Between 2005 and 2014, the Medica...

In Patients With PAD, Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine

Jun 17, 2022

Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was associated with high morbidity in patients with predominant antibody deficiency (PAD).  For a study, researchers so...

Mutations of Filaggrin Leading to Eggs & Milk Allergies

Jun 17, 2022

The origin of eczema and allergic airway illnesses was linked to a hereditary deficiency in the epidermal barrier protein filaggrin. For a study, researchers sought to find a link between filaggrin ge...

Ground-Glass Opacity Predominant Lung Cancer After SBRT

Jun 16, 2022

For a study, researchers sought to assess GGOp-LC early-phase CT findings following SBRT. Patients with GGOp-LC staged as cTis-2bN0M0 who received SBRT were identified retrospectively. Radiologists' i...

In Children & Adults With Allergic Asthma, Cluster Analysis of Nasal Cytokines During Rhinovirus Infection Identifies Different Immunophenotypes

Jun 16, 2022

For a study, researchers sought to look at a wide range of cytokines in the noses of children and adults with asthma during RV infection to see if there were any immunophenotypes linked to virus-induc...

Anti-Peanut Antibody Responses in Children With Peanut Allergies

Jun 10, 2022

For a study, researchers sought to see how PPOIT (Probiotic and Peanut Oral Immunotherapy) affected peanut-specific humoral immunological indices and how such longitudinal indices were related to SU (...

The Ability of Allergen-Specific Immunoglobulin G, F(ab')2, & Fab Antibodies Prepared from Dermatophagoides Pteronyssinus Immunotherapy Patients

Jun 10, 2022

The blocking ability of allergen-specific F(ab')2 [sF(ab')2] and Fab (sFab) fragment antibodies derived from allergen immunotherapy–induced specific immunoglobulin G (sIgG) has yet to be completely ...

Early RA Synovium Shows Complement Activation vs. Regulatory Protein Imbalance

Jun 10, 2022

Rheumatoid arthritis (RA) is an autoimmune illness marked by inflammation and synovial hyperplasia. Because of the local presence of immune complexes in the joints, autoantibodies in seropositive RA s...

In Immune-Mediated Thrombocytopenic Purpura, Naturally Occurring Anti-Idiotypic Antibodies Reveal A Primarily Personal Repertoire.

Jun 10, 2022

A severe autoantibody-mediated ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motifs, member 13) deficiency caused immune-mediated thrombotic thrombocytopenic purpura (iTTP), a...

Association Between IgG N-glycosylation & Rheumatoid Arthritis

Jun 10, 2022

Observational studies have linked IgG N-glycosylation to rheumatoid arthritis (RA), but the causal relationship between the 2 illnesses has yet to be established. To investigate the possible causal co...

Tepotinib Safety & Management: MET Exon 14 Skipping NSCLC

Jun 08, 2022

Researchers thoroughly analyzed adverse events of clinical interest (AECIs) in the VISION trial, including edoema, a MET inhibitor class effect. For patients with MET Exon 14 skipping NSCLC in the pha...

The Burden of Food Allergy on Children & Teens

May 25, 2022

Over the last two decades, researchers have paid more attention to how food allergies affect children's and teens' health-related quality of life (HRQL) and psychological well-being. In response, seve...

Child Filaggrin Mutations & Maternal Diet With the Development of Allergic Diseases

May 25, 2022

For a study, researchers sought to investigate whether Filaggrin (FLG) mutations alter the effect of maternal nutrition on the risk of allergy illness development. "Which factor, maternal nutrition or...

The Role of Respiratory Syncytial Virus-& RV-Induced Bronchiolitis in Recurrent Wheeze & Asthma

May 25, 2022

Bronchitis was most commonly caused by the respiratory syncytial virus (RSV). In cohort studies with healthy newborns as reference groups, RSV-induced bronchiolitis was linked to preschool wheezing an...

Safety & Efficacy of Rapid Drug Desensitization (RDD) in Children

May 25, 2022

Hypersensitivity responses can occur with any medicine when taken at the recommended dosage (DHR). For a study, researchers sought to assess the features of desensitized children, the safety and effic...

Metabolomics Analysis : Molecular Linkages for Vitamin D's Impact on Allergic Airway Diseases

May 25, 2022

A metabolomics-based approach to the effects of vitamin D on allergic reactions was still unknown. A total of 111 children were enrolled and categorised based on their longitudinal vitamin D status (...

Organ-Specific Symptom Patterns During Oral Food Challenges (OFC) in Children

May 25, 2022

For a study, researchers sought to investigate the distribution of clinical symptoms and their intensity in children during oral food challenges (OFC). Peanut (n=607), hazelnut (n=266), walnut (n=97),...

Gene Expression in Nasal Airway Epithelium From Overweight or Obese Youth With Asthma

May 25, 2022

For a study, researchers sought to discover differentially expressed genes and pathways linked to obesity-related asthma by using a transcriptome study of nasal airway epithelium. Using RNA sequencing...

Age-Specific Associations of Early Daycare, Severe Airway Infection, & Preterm Birth With Atopic Diseases

May 25, 2022

For a study, researchers sought to compare and contrast the age-specific associations of asthma, allergic rhinitis/conjunctivitis, and atopic dermatitis in children with early-life infection-related f...

Airflow Limitation in Asthma: Post-hoc Analyses of TRIMARAN & TRIGGER

May 25, 2022

For a study, researchers sought to look at the connection between post-salbutamol Persistent airflow limitation (PAL) at screening, airflow limitation (AL) during 52 weeks of extra-fine beclometasone ...