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Allergy & Immunology General

Airflow Limitation in Asthma: Post-hoc Analyses of TRIMARAN & TRIGGER

May 25, 2022

For a study, researchers sought to look at the connection between post-salbutamol Persistent airflow limitation (PAL) at screening, airflow limitation (AL) during 52 weeks of extra-fine beclometasone ...

Effects of Anti-IL5 Biological Treatments on Blood IgE Levels in Severe Asthmatic Patients

May 25, 2022

Mepolizumab and benralizumab were biological therapies that reduced eosinophilic inflammation in severe eosinophilic asthmatic patients. For a study, researchers sought to see how total IgE levels bet...

Examining the impact of multilevel upper airway surgery on the obstructive sleep apnoea endotypes and their utility in predicting surgical outcomes.

May 23, 2022

Upper airway surgery for obstructive sleep apnoea (OSA) is an alternative treatment for patients who are intolerant of continuous positive airway pressure (CPAP). However, upper airway surgery has var...

MANDALA Patterns Success for Albuterol-Budesonide in Asthma

May 18, 2022

In patients with uncontrolled moderate-to-severe asthma, the risk of asthmatic exacerbation was significantly reduced when patients used a fixed-dose inhaler with a combination of albuterol and budeso...

Growth in Diagnosis & Treatment of Primary Immunodeficiency (PI) Within the Global JMCN

May 10, 2022

For a study, researchers sought to promote awareness of primary immunodeficiencies (PI) so that patients might be better identified, diagnosed, and treated, lowering mortality and morbidity and enhanc...

Association Between Depression & Mortality in Patients With Asthma

May 10, 2022

For a study, researchers sought to find how depression affected asthmatic patients' mortality among adults in the United States. The National Health and Nutrition Examination Survey (NHANES) data from...

Adult Allergy Outcomes & Sleep Disorders

May 10, 2022

For a study, researchers sought to find a link between sleep disturbances and allergy-related outcomes in adults. Using the 2005–2006 NHANES database, they created logistic regression models to inve...

Outcome of a De-labelling Algorithm Compared With Penicillin (β-lactam) Allergy Testing Results

May 10, 2022

Guideline-directed treatment with penicillin or other β-lactam antibiotics is commonly hampered by penicillin allergy labeling. For a study, researchers sought to test a standardized approach to dist...

Comparison of Circulating Fibrocytes From Non-Asthmatic Patients With Seasonal Allergic Rhinitis Between in & Out of Pollen Season

May 10, 2022

Allergic rhinitis is linked to the development of asthma. Following allergen exposure, fibroblast progenitors, or fibrocytes, are increased in the blood and bronchial mucosa in asthma. As shown in non...

Linear Epitope Binding Patterns of Grass Pollen-Specific Antibodies in Allergy & in Response to AIT

May 10, 2022

Allergen-specific immunotherapy (AIT) could affect disease progression by inducing allergen-specific IgG that blocks allergen-IgE interactions. Epitopes identified by allergy-causing and protective an...

Progressive Egg Tolerance Induction in Hen's Egg Allergy Children Tolerating Baked Egg

May 10, 2022

In past years, research showed that most egg-allergic youngsters tolerate baked eggs (for example, cake) and that eating baked eggs speeds up the resolution of egg allergy. For a study, researchers so...

Tolerance Predicted By Intradermal Testing With COVID-19 mRNA Vaccines

May 10, 2022

The newly created mRNA-based COVID-19 vaccines have the potential to cause anaphylaxis, which could be triggered by the vaccine's polyethylene glycol (PEG).  For a study, researchers defined 2 cohort...

Beta-Lactam Antibiotic Allergy Management

May 10, 2022

Beta-lactam allergy was a prevalent problem in regular medical practice and was recognized as a significant public health concern. For a study, researchers looked back at the clinical records of 576 p...

Granulocyte-Colony Stimulating Factor: Stratification of Type 2–High & Low Chronic Rhinosinusitis (CRS) Patients

May 10, 2022

For a study, researchers sought to discover the underlying molecular pathways of type 2–low chronic rhinosinusitis (CRS) with the hope of improving tailored therapy by stratifying patients. Proteins...

Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model.

May 09, 2022

Monoamine oxidase (MAO) inhibitors have been investigated for the treatment of neuropathic pain. Here, we assessed the antiallodynic effects of a novel MAO-B inhibitor, KDS2010, on paclitaxel (PTX)-in...

Risk factors for asthma in patients with allergic rhinitis in eastern China.

Apr 25, 2022

Asthma is one of the most common chronic diseases among children and adults and can lead to a high health and socioeconomic burden. Allergic rhinitis (AR) often precedes the development of asthma. Thi...

Anti-Phospholipid Antibodies Are Elevated & Functionally Active in Chronic Rhinosinusitis (CSR) With Nasal Polyps

Apr 22, 2022

For a study, the researchers sought to examine whether NP antibodies affected coagulation and correlated APAs with anti-dsDNA IgG and coagulation markers in nasal polyp (NP) tissue with tissue from co...

Down-Regulated Surfactant Protein B (SP-B) in Obese Asthmatics

Apr 22, 2022

Because of the critical role of hydrophobic surfactant protein B (SP-B) in lung function, SP-B was researched in asthmatics to determine if it had a role in developing obesity-induced airway inflammat...

Efficacy of NAAGA Vs Fluorometholone For Treating Allergic Conjunctivitis in an EEC

Apr 22, 2022

During controlled exposures to the airborne birch pollen allergen, Bet v 1, in an environmental exposure chamber (EEC), researchers assessed the non-inferiority of a topical mast cell stabilizer, N-ac...

Mast Cell Activation Test: A New Asset in The Investigation of The Chlorhexidine (CHX) Cross-Sensitization Profile

Apr 22, 2022

For a study, researchers sought to determine if combining the passive mast cell activation (pMAT) with CHX-specific IgE (sIgE) allowed us to display effector cell degranulation in response to alexidin...