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Hepatitis

Multiclass identification of hepatitis C based on serum Raman spectroscopy.

Mar 20, 2020

Hepatitis C is a chronic infectious disease, and early detection and diagnosis are key to curing it. In this study, human serum Raman spectroscopy combined with a support vector machine (SVM) classifi...

[Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape].

Mar 20, 2020

Infectious diseases continue to play an important role for disease perception, health-economic considerations and public health in Germany. In recent years, infectious diseases have been linked to the...

An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein.

Mar 12, 2020

A vaccine protective against diverse HCV variants is needed to control the HCV epidemic. Structures of E2 complexes with front layer-specific broadly neutralizing antibodies (bNAbs) isolated from HCV-...

Does a change in quality control results influence the sensitivity of an anti-HCV test?

Mar 09, 2020

Background Laboratories use quality control (QC) testing to monitor the extent of normal variation. Assay lot number changes contribute the greatest amount of variation in infectious disease serology ...

Examining risk behavior and syringe coverage among people who inject drugs accessing a syringe services program: A latent class analysis.

Mar 09, 2020

Injection drug use (IDU) remains a significant public health problem. IDU has been associated closely with the opioid crisis; driving overdose, HIV, and Hepatitis C (HCV) infection nationwide. Syringe...

The Conundrum of an Accumulating Acuminatum.

Mar 02, 2020

BACKGROUND A 70-year-old African American man presented with fatigue, dizziness, generalized weakness, and considerable weight loss of over 20 pounds in 3 weeks. History-taking revealed he was positiv...

[Dramatic achievements in infectious disease prevention and treatment in China during the past 70 years].

Feb 28, 2020

At the beginning of the founding of People's Republic of China, infectious diseases, such as smallpox, plague, cholera, dysentery, typhoid, measles, diphtheria, pertussis, meningitis, mumps, schistoso...

A Bayesian classification model for discriminating common infectious diseases in Zhejiang province, China.

Feb 28, 2020

To develop a classification model for accurately discriminating common infectious diseases in Zhejiang province, China.Symptoms and signs, abnormal lab test results, epidemiological features, as well ...

The Conundrum of an Accumulating Acuminatum

Feb 28, 2020

BACKGROUND A 70-year-old African American man presented with fatigue, dizziness, generalized weakness, and considerable weight loss of over 20 pounds in 3 weeks. History-taking revealed he was positiv...

All together now: aggregating multiple records to develop a person-based dataset to integrate and enhance infectious disease surveillance in Ontario, Canada.

Feb 28, 2020

Syndemics occur when two or more health conditions interact to increase morbidity and mortality and are exacerbated by social, economic, environmental, and political factors. Routine provincial survei...

Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases.

Feb 28, 2020

Abundant evidence points to a critical role for antibodies in protection and pathology across infectious diseases. While the antibody variable domain facilitates antibody binding and the blockade of i...

Community viral load and hepatitis C virus infection: Community viral load measures to aid public health treatment efforts and program evaluation.

Feb 13, 2020

Hepatitis C virus (HCV) infection is the most prevalent blood-borne infection and causes more deaths than any other infectious disease in the US. Incident HCV infection in the US increased nearly 300 ...

Applying a Constrained Optimization Portfolio Model to Aid Prioritization of Public Health Interventions in Malaysia.

Feb 13, 2020

Countries have constrained healthcare budgets and must prioritize new interventions depending on health goals and time frame. This situation is relevant in the sphere of national immunization programs...

Design and Development of a Viral Hepatitis and HIV Infection Screening Program (Hprolipsis) for the General, Greek Roma, and Migrant Populations of Greece: Protocol for Three Cross-Sectional Health Examination Surveys.

Feb 11, 2020

Although infectious diseases are globally on the decline, they remain a major global public health problem. Among them, the hepatitis B virus (HBV) or hepatitis C virus (HCV) and HIV infection are of ...

Community Viral Load and Hepatitis C Virus Infection

Feb 11, 2020

Hepatitis C virus (HCV) infection is the most prevalent blood-borne infection and causes more deaths than any other infectious disease in the US. Incident HCV infection in the US increased nearly 300 ...

Evaluating the Effect of Standard of Care Treatment on Burden of Chronic Hepatitis B: A Retrospective Analysis of the United States Veterans Population.

Feb 11, 2020

This study aimed to characterize chronic hepatitis B (CHB)-infected patients and estimate the association between nucleos(t)ide analogue (NA) persistence and economic outcomes using data from the Vet...

Serological Survey on Bacterial and Viral Pathogens in Wild Boars Hunted in Tuscany.

Feb 11, 2020

Wild boar (Sus scrofa) is one of the large mammals most spread worldwide, including Italy. This animal is highly adaptable, and its population has rapidly increased in many areas in Europe. Central It...

Trends in Hepatitis A Infection

Jan 15, 2020

Although reported cases of hepatitis A virus (HAV) decreased significantly following availability of the HAV vaccine in 1996, increases observed in HAV cases since 2016 may be a sign that at-risk indi...