Patients requiring long-term parenteral feeding must have consistent venous access (PN). Central venous catheters, on the other hand, represent a significant risk factor for the development of potentially fatal consequences, such as catheter-related bloodstream infection (CRBSI). We examined the incidence of CRBSIs in children on long-term PN who were treated at the Children’s Hospital Zagreb between January 2011 and January 2019, as well as the economic efficacy of using taurolidine line locks in children on home PN (HPN). During this time, 48 children were given long-term PN, while 24 were released to HPN. 

CRBSI occurred at an incidence of 1.15/1000 catheter days overall, 2.35/1000 days in the hospital, and 0.48/1000 days at home. If taurolidine line lock was used every day of PN for children with HPN, the overall expenses would be more than five times more than the current CRBSI treatment costs.