Children who have received an influenza vaccine are less likely to have symptomatic COVID-19 or severe disease, according to a study published in Cureus. Researchers examined the effect of influenza and pneumococcal vaccines on the disease course among SARS-CoV-2 patients aged 20 and younger who visited Arkansas Children’s Hospital System between February 1 and August 30, 2020. Viral interference may have played a role in the flu and COVID-19 twindemic. Comparing SARS-CoV-2-positive patients who had been vaccinated versus those who had not been vaccinated for influenza showed that patients who were vaccinated had lower odds of having symptomatic diseases (odds ratio [OR], 0.714). Patients who received the pneumococcal vaccine also had lower odds of having symptomatic disease than those who were unvaccinated (OR, 0.482). Compared with patients who were not vaccinated, patients who were vaccinated for influenza had lower odds of having respiratory symptoms (OR, 0.678). Patients vaccinated for influenza and pneumonia had lower odds of severe disease than those not vaccinated (ORs, 0.672 and 0.412, respectively).