The study aims to evaluate major urological interventions during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in complex abdominal malignancies with peritoneal carcinomatosis.

Forty-four cases underwent surgical intervention related to the urinary system among 208 subjects who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy because of peritoneal carcinomatosis.

Urinary system resections were performed during cytoreductive surgery in a total of 44 cases. The mean age was 54 years. Patients were diagnosed with peritoneal carcinomatosis due to colorectal cancer in 21, ovarian cancer in nine, sarcomatosis in five, cervical cancer in four, and other cancers in five cases. Total nephrectomy was performed in three patients and partial nephrectomy at one point. Cystectomy was performed in 21 cases; 16 of these were partisan, and five were total cystectomies. Ureteroureterocystostomy with double J was conducted in four instances, and ureteroneocystostomy in 12 cases. While Clavian–Dindo grade 3–4 complications were seen in nine points, three patients became exitus during the first 30-day follow-up.

The study concluded that with adequate experience, radical urinary interventions performed in suitable patients could be carried out with acceptable morbidity and mortality, as seen in our series.