Cochlear implantation among adults with single-sided deafness (SSD) significantly improved speech perception, tinnitus control, sound localization, and QOL, according to findings published in Otolaryngology-Head and Neck Surgery. Maura Cosetti, MD, and colleagues analyzed 50 studies with a total of 674 patients to determine clinical outcomes among adult patients with SSD receiving ipsilateral cochlear implants. They observed significant improvements in speech perception scores in quiet and noise, tinnitus control, sound localization, and QOL following implantation. Pooled outcomes showed better scores in speech perception (standardized mean difference [SMD], 2.8 [95% CI, 2.16-3.43]), QOL (SMD, 0.68 [95% CI, 0.45-0.91]), sound localization (SMD, −1.13 [95% CI, −1.68 to −0.57]), and decreased tinnitus score (SMD, −1.32 [95% CI, −1.85 to −0.80]).