This study was done with the purpose to compare the anatomical and visual outcomes of vitrectomy with the ILM peeling alone versus inverted ILM flap to plug the pit versus autologous scleral plug for the treatment of ODP-M.

This was basically a retrospective study. The research included 23 patients with one eye each who underwent 25G pars plana vitrectomy, ILM peeling, and gas tamponade.

Baseline characteristics were similar in all three groups so that the findings are not affected by the individual differences. Mean central foveal thickness and SRF were observed to be decreased in all three groups. Complete anatomical success was achieved in 25.0%, 85.7%, and 87.5% eyes while visual success was achieved in 12.5%, 28.6%, and 12.5% eyes in groups 1, 2, and 3, respectively. One eye in group 2 developed a full-thickness macular hole at 1-month post-surgery. After complete resolution, there was no recurrence of fluid.

This study concluded through its findings that the OPD-M has a better surgical outcome if the pit is plugged. Both inverted ILM flap and autologous scleral plug are equally efficacious adjuncts to plug the pit.

Reference: https://bjo.bmj.com/content/104/11/1567

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