The goal of this study was to identify risk factors for postoperative death in individuals who have tested positive for Coronavirus Disease 2019 (COVID-19). COVID-19 positive patients are more likely to experience problems after surgery. However, there is a lack of research into the causes of postoperative death in COVID-19-positive patients. Patients who tested positive for COVID-19 and who received elective surgical or other procedures at Cleveland Clinic between January 2020 and March 2021 were identified retrospectively. The mortality rate at 30 days after surgery or procedure was the primary endpoint. There were also secondary outcomes, such as length of stay, ICU admission, and 30-day readmission rates.

There were a total of 2,543 patients with a total of 3,027 surgical and/or procedural operations. Men made up nearly half of the patients or 48.5%. An average of 57.8 (or 18.3) years had passed. About 1 or more co-occurring disorders affected 71.2% of the sample. A total of 78.7% of the procedures were voluntary. The average length of stay was 6.43 (13.4) days, and the median length of time an operation took was 94 (47.0-162). The death rate after surgery or other medical procedures was 4.01%. [Odds ratio (OR): 1.66, 95% CI, 1.4-1.98; P<0.001]; [older age; 2.76, (1.3-5.82); P=0.008]; [current smoking status; 3.22, (1.03-10.03); P=0.043]; [presence of comorbidity; 6.35, (3.39-11.89); P<0.00]; [emergency versus urgent versus [1.78, (1.12-2.84); P=0.015]. Multivariate analysis revealed an increased risk of death for patients who had elective surgery, were admitted through the emergency department [15.97, (2.00-127.31); P=0.009], or were hospitalized rather than treated as outpatients [32.28, (7.75-134.46); P<0.001].

The largest mortality relationship was found in thoracic surgery [3.76, (1.66-8.53); P=0.002]. With a body mass index of 1.03 (95% CI: 1.01-1.05) and a P=0.005, 17.5%), the patients required admission to the critical care unit. Patients who test positive for COVID-19 are at a higher risk of dying after surgery. Before taking any preventative measures, it is important to assess potential sources of risk thoroughly. The effects of pandemics on the long-term success of surgical and procedural outcomes need more research.