The origin of IHPS is unclear, however, numerous risk factors have been identified. The goal of this study was to examine the prevalence of recognized risk factors and to look into maternal diet and behaviors as potential new risk factors for IHPS. This case-control research included mothers of infants diagnosed with IHPS and control moms of infants hospitalized in the pediatric department for various reasons, ranging in age from 2 to 11 months. Cases of IHPS were discovered by a study of all babies diagnosed with IHPS and operated on at two large hospitals in central Israel from 2010 to 2016. In both research groups, questionnaires were used to collect information on possible risk factors. In the research, 66 cases and 67 controls were included. Maternal omega-3 supplementation during pregnancy was substantially less prevalent in IHPS patients compared to controls. Consumption of omega-3 supplements was classified as at least one to two per week throughout pregnancy. After controlling for established risk variables such as male sex and maternal smoking, maternal omega 3 supplement intake was shown to be related to a substantially reduced chance of developing IHPS.

Maternal omega-3 supplementation during pregnancy was related to a substantially lower risk of IHPS. More research is needed to back up these findings and look into the probable mechanisms of omega 3’s influence.