The notion of precision medicine is both enticing and difficult. We will go through the most current results in the endotype-driven approach to major allergy disorders. Stratified medicine for various allergic illnesses can identify individuals who are more likely to benefit or have an unfavourable reaction to a particular medication and predict their long-term prognosis and critical risk. Furthermore, this method has the potential to assist drug development and preventive efforts.

Although the endotype-driven approach in allergic disorders has enormous potential, there are many hurdles to entering the new realm of precision medicine. For both type 2 and non-type 2 allergic disorders, multidimensional endotyping combining visual features with numerous biomarkers is advised to offer proof that a certain route is the primary driver for a given patient. Significant reforms to the healthcare system are necessary to meet the projected objectives.