Allergic diseases are caused by complicated combinations between genetic predisposition and environmental exposure. Therefore, it was critical to understand how particular environmental exposures led to allergy disorders in adults, especially as the world population ages in a constantly changing environment. The impact of environmental exposures on allergy disorders in adults was still being explored. Although epidemiological studies implied that numerous environmental exposures were linked to the development and worsening of allergy disorders, more longitudinal research in adults across various age groups was needed to define the exposures of concern and the time windows of vulnerability. There have been few mechanistic investigations in adults. Although a multicomponent strategy addressing several allergens was conditionally suggested for asthma, recent studies on mitigation techniques were limited.

More study was needed in adults to understand how environmental exposures induce and aggravate allergy diseases, particularly across disease subtypes. There were significant study gaps in the impact of mitigation methods against environmentally generated adult allergy disorders. To identify patients at higher risk and who might benefit from specific therapies, a better knowledge of how and which environmental exposures contribute to allergic diseases was required.

 

Source:journals.lww.com/co-allergy/Abstract/2022/02000/Environmental_exposures__evolving_evidence_for.5.aspx