The main objective of this article is to perform and understand that how The indication of epilepsy prevention after central nervous system diseases should be considered according to the frequency and severity of the seizure and adverse effects of antiepileptic drugs. Bodilsen and colleagues reported that 32% of 30-day survivors of brain abscess developed new-onset epilepsy [1]. This result suggests that epilepsy is a relatively frequent complication of brain abscess, and the indication of prevention is worth discussing. However, several additional points should be incorporated into this discussion.

First, the proportion of refractory epilepsy among new-onset epilepsy after brain abscess should be presented. The drugs used to treat new-onset epilepsy should also be investigated.

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