TUESDAY, Feb. 12, 2019 (HealthDay News) — Incident fragility fractures are associated with long-term impacts on health-related quality of life (HRQOL) in older people, according to a study published online Feb. 5 in the Journal of Bone and Mineral Research.

Sayem Borhan, from McMaster University in Hamilton, Ontario, Canada, and colleagues used 10-year prospective data from the Canadian Multicentre Osteoporosis Study to evaluate the impact of incident fragility fractures on HRQOL among 7,753 adults aged ≥50 years.

The researchers found that incident spine and hip fractures were associated with significant deficits in Health Utility Index scores. Hip and spine fractures were associated with a negative impact on mobility, self-care, and ambulation. Compared with fractures occurring a long time before assessment, fractures that occurred closer to the follow-up assessment were associated with a significant impact on HRQOL, with the exception of hip fractures (deficits lasted at least five years). In women, multiple hip, spine, and rib fractures significantly impacted HRQOL. For women with a hip fracture, recovery to their prefracture-level score did not occur (odds ratio, 0.41).

“Our analysis suggests that single and multiple hip fractures as well as multiple spine and rib fractures strongly impact the HRQOL of older people over a prolonged period of time,” the authors write.

Several authors disclosed financial ties to pharmaceutical companies.

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