Dumping syndrome (DS) is commonly characterized as a consequence of antireflux surgery in children with oesophageal atresia (OA), however, researchers previously reported two cases of DS before any other surgery in infants with OA who were operated on at birth. The goals of this study were to determine the prevalence of abnormal oral glucose tolerance test (OGTT) at 3 months of age in children with type C OA who were operated on at birth, to characterize symptoms and clinical characteristics, and to analyze risk factors in infants with abnormal OGTT indicative of DS. A prospective case series research was carried out in 8 centers, involving babies with type C OA without fundoplication born between 2013 and 2016. Between 2.5 and 3.5 months, an OGTT was done. Early hyperglycemia and/or late hypoglycemia were classified as abnormal OGTT results. Eleven of the 38 OGTTs were found to be abnormal. There was no correlation between abnormal OGTT and any of the patients’ demographics or surgical conditions examined. There was no particular clinical symptom for it.

Every infant who is operated on at birth for OA and has digestive problems should be evaluated for DS. There were no risk factors that predicted an abnormal OGTT. In infants born with EA, an OGTT to test for possible DS around 3 months of age should be explored.