Fundoplication is a frequent paediatric operation, however it might cause vague symptoms that should be evaluated further. The purpose of this study was to compare the Functional Luminal Imaging Probe (FLIP) to high-resolution manometry with impedance (HRIM) in the assessment of fundoplication symptoms. Researchers examined FLIP and HRIM tracings from individuals with symptomatic fundoplication. FLIP findings from fundoplication patients were compared to those from paediatric achalasia and control patients. In addition, they evaluated FLIP’s function in clinical decision-making and clinical outcomes to those of HRIM. Fundoplication patients’ EGJ distensibilities varied from 0.6 to 8.2 mm2/mmHg. Balloon size inflations varied due to the diverse paediatric patient sizes, however after correcting balloon fill volume by weight, there was a linear connection between inflation and distensibility. When compared to control and achalasia patients, fundoplication patients had lower distensibilities and greater achalasia distensibilities. EGJ intervention patients exhibited a mean EGJ distensibility of 2.3 1.1 mm2/mmHg compared to 5.1 1.6 mm2/mmHg in medically treated patients. Patients who received an esophagogastric junction (EGJ) intervention had a mean IRP of 13.9 6.1 mmHg compared to 9.9 3.9 mmHg in medically treated patients.

FLIP may give further information into EGJ physiology in individuals with symptomatic fundoplication and complements HRIM.

Reference:https://journals.lww.com/jpgn/Fulltext/2020/06000/Functional_Luminal_Imaging_Probe_Assessment_in.22.aspx

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