This study states that Shiga poison creating Escherichia coli (STEC) O80:H2 has arisen in Europe as a reason for hemolytic uremic disorder related with bacteremia. STEC O80:H2 harbors the mosaic plasmid pR444_A, which joins a few harmfulness qualities, including hlyF and antimicrobial opposition qualities. pR444_A is found in some extraintestinal pathogenic E. coli (ExPEC) strains. We recognized and described 53 STEC strains with ExPEC-related harmfulness qualities segregated in Italy and the Netherlands during 2000–2019. The detaches have a place with 2 significant populaces: 1 has a place with succession type 301 and harbors assorted stx2 subtypes, the intimin variation eae-ξ, and pO157-like and pR444_A plasmids; 1 comprises of strains having a place with different arrangement types, some of which do not have the pO157 plasmid, the locus of enterocyte destruction, and the antimicrobial obstruction encoding locale. Our outcomes showed that STEC strains holding ExPEC-related harmfulness qualities can incorporate numerous serotypes and that the pR444_A plasmid can be obtained and assembled by STEC strains.

Shiga poison delivering Escherichia coli (STEC) is a gathering of enteric microorganisms that cause foodborne illness going from straightforward loose bowels to hemorrhagic colitis (HC) or hemolytic uremic disorder (HUS) (1). The most genuine difficulty of STEC disease is HUS, which can be lethal.

Reference link- https://wwwnc.cdc.gov/eid/article/27/3/20-3110_article