The goals of this study were to determine the serum levels of iron, zinc, and copper in children with Helicobacter pylori infection who were experiencing symptoms, to determine whether or not these serum levels correlated with the severity of gastritis, and to assess the impact of H. pylori infection on these variables. In addition, treatment for pylori according to the individual’s personality. A total of 70 young people with esophageal or gastric-related complaints participated in the study. H. pylori testing confirmed the presence of the infection. The results of a stool test for H. pylori antigen and a histopathologic examination of the upper digestive tract.

The patients were divided into 2 groups; H. pylori-positive and H. pylori-negative for Helicobacter pylori, all included kids who had their iron, copper, zinc, and sTfR levels checked. Compared to others, H had significantly lower hemoglobin, serum ferritin, and zinc concentrations. patients who test positive for H. pylori versus those who test negative for the bacteria. patients who test negative for H. pylori. On the other hand, there was no discernible difference in the amount of copper in the serum between the 2 groups. After treatment, there was a notable rise in histopathologic abnormalities and hemoglobin level, serum ferritin level, and zinc level. patients with H. pylori positivity, and more so in those who improved after treatment.

The severity of histopathologic abnormalities correlated negatively with hemoglobin, serum ferritin, and zinc levels but positively with sTfR concentrations in patients who tested positive for H. pylori. Children infected with Helicobacter pylori exhibited low serum ferritin and zinc levels but high sTfR levels, with no change in blood copper levels. Hemoglobin, serum ferritin, and zinc all increased markedly after treatment in patients who tested positive for Helicobacter pylori. Hemoglobin, serum ferritin, zinc, and soluble transferrin receptor levels strongly correlated with gastric histologic findings.

Source: journals.lww.com/jpgn/Abstract/2022/11000/Study_of_Serum_Ferritin,_Zinc,_and_Copper_Levels.5.aspx