It is unclear what role daughters play in the decision-making process regarding HPV vaccination. Therefore, we explored the impact of HPV vaccination intention among parents and their 12–13-year-old daughters on HPV vaccination uptake.

In total, 273 Dutch parent-daughter dyads and 165 non-Dutch dyads were analyzed for this study. HPV vaccination uptake was 90% and 84% (139/165) in the Dutch and non-Dutch groups. High parental intention and high daughters’ intention were significantly associated with HPV vaccination uptake in the Dutch group. In the non-Dutch group, high daughters’ purpose (β = 1.2, 95%CI 0.16–2.2) was significantly associated with HPV vaccination, but the high parental intention was not. The attitude was the most prominent socio-psychological determinant associated with vaccination intention among all groups.

In the non-Dutch group, only the daughters’ intention was significantly associated with HPV vaccination uptake. In contrast, in the Dutch group, both the parents’ and the daughters’ purpose were significantly associated with uptake. The child’s role in the decision-making process might need to be considered when developing new interventions focused on increasing HPV vaccination uptake, especially among individuals of non-Dutch origin.