This study states that Around 10–25% of patients with foundational lupus erythematosus (SLE) made do with antimalarials will foster cutaneous hyperpigmentation, and albeit most of such cases is credited to chloroquine, hydroxychloroquine (HCQ) is additionally embroiled and is likely underrecognized1.
A 52-year-old Hispanic lady with SLE and endstage renal illness accepting peritoneal dialysis gave a 3-month history of asymptomatic, reformist obscuring of her respective furthest points. There was no precursor injury or going before skin emission. She had been taking HCQ 200 mg day by day for a very long time. Actual assessment uncovered diffuse mottled and reticular hyperpigmentation with neighboring spaces of ecchymosis on the two-sided furthest points. A biopsy uncovered dermal stores of iron and melanin. A finding of medication actuated dyschromia was made with a staining design viable with that of antimalarial openness.
Reference link- https://www.jrheum.org/content/47/11/1721
