This study was done with the purpose to investigate the IgE level in the newborn’s umbilical cord blood and its relationship with some maternal factors.
A cross-sectional study was conducted on 101 mothers and their newborns in Babol, Iran 2016. The samples were selected using non-probability convenience sampling. Information including newborn sex, gravidity, history of allergy before and during pregnancy, family history of allergy among mothers, history of exposure to secondhand smoke and pets, and delivery techniques was recorded. The IgE levels in newborn umbilical cord blood and maternal serum were measured using an IgE kit and ELISA technique.
The newborns included 53 females and 29 mothers had a vaginal birth. History of exposure to secondhand smoke was found in 15 samples, and 18 participants reported exposure to pets. The median IgE levels in newborns and their mothers were 0.41 and 98.6, respectively. In general, the IgE level in all newborns was within the normal range, but, it was higher than normal in 15 mothers.
The study concluded through its findings that the IgE level in all newborns was within the normal range, and sex was found to be an effective factor in IgE levels.
Reference: https://clinicalmolecularallergy.biomedcentral.com/articles/10.1186/s12948-019-0115-1
