The purposes of this study were to compare physical activity(PA) in a group of psoriatic arthritis(PsA) patients versus healthy controls and to determine whether the mobility of these patients is affected by disease activity. A group of 52 PsA patients and 53 controls were included in this case‐control study. PA was assessed by accelerometry in both groups and the International Physical Activity Questionnaire(IPAQ) in PsA patients. Multiple regression analysis was used to compare PA between groups and determine the relationship between PA and PsA features, including disease activity, as assessed by Disease Activity Score(DAS)28 and Disease Activity Index for Psoriatic Arthritis(DAPSA). In a group of 36 patients, a test‐retest study was carried out after six months.

Time engaged in moderate and vigorous activity(MVPA)/day, as evaluated by accelerometry, and adjusted by confounders, proved similar in PsA patients and controls. In PsA patients, disease activity was inversely related to PA as assessed either by IPAQ or accelerometry. When PA was compared in PsA patients between the two visits, a significant difference in the amount of time doing MVPA was found (42±33 vs. 30±22 min/day,p=0.004). Interestingly, in the test‐retest study, variations in disease activity over time, based on DAPSA (r=‐0.49,p=0.002) and DAS28‐PCR (r=‐0.4,p=0.017) were inversely correlated with changes in PA, as determined by accelerometry.

PsA patients show levels of PA like healthy controls. In PsA patients, disease activity and PA are inversely correlated, and the evaluation of PA by accelerometry is sensitive to changes in disease activity.