This coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first detected in January 2020 and has spread throughout the country. With the COVID-19 pandemic still ongoing, the annual season of influenza and other respiratory virus epidemics has arrived. Previous studies have reported that viral interference among influenza virus, rhinovirus, and other respiratory viruses can affect viral infections at the host and population level.1, 2 To investigate the effect of COVID-19 on these virus infections, we analyzed clinical specimens collected from patients in Japan with respiratory diseases from January 2018 through September 2020. Respiratory specimens (nasal swab, throat swab, nasal discharge, saliva, tracheal aspiration fluid, or sputum) were collected from 2244 patients with respiratory diseases in Yokohama, Japan, from January 2018 through September 2020 as part of the National Epidemiological Surveillance of Infectious Diseases and the Active Epidemiological Investigation for COVID-19 in Japan. Influenza virus,3 rhinovirus, and other respiratory viruses (coxsackievirus A and B4; echovirus4; enterovirus4; human coronavirus 229E, HKU1, NL63, and OC43; human metapneumovirus; human parainfluenza virus 1, 2, 3, and 4; human parechovirus5; human respiratory syncytial virus; human adenovirus6, 7; human bocavirus; human parvovirus B198; herpes simplex virus type 1. 

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