Here are what the editors at HealthDay consider to be the most important developments in Nephrology for July 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Burnout Symptoms May Up Racial Bias Among Resident Physicians

WEDNESDAY, July 31, 2019 (HealthDay News) — Symptoms of burnout seem to be associated with greater explicit and implicit racial bias among resident physicians, according to a study published online July 26 in JAMA Network Open.

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Preeclampsia History Increases Risk for End-Stage Kidney Disease

WEDNESDAY, July 31, 2019 (HealthDay News) — Women with preeclampsia have an increased risk for developing end-stage kidney disease (ESKD), according to a study published online July 30 in PLOS Medicine.

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$70 Million Settlement Reached in Generic Drug Delay Case

TUESDAY, July 30, 2019 (HealthDay News) — Three drug companies will pay a total of nearly $70 million to California to settle charges of delaying the sale of generic drugs to keep brand-name drug prices high, the state’s attorney general said Monday.

AP News Article

National Norms Developed for Assessing Medical School Empathy

TUESDAY, July 30, 2019 (HealthDay News) — National norms have been developed for assessing empathy among men and women at different levels of medical school education, according to a study published in the August issue of the Journal of the American Osteopathic Association.

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Roxadustat Noninferior to Epoetin Alfa in Dialysis Patients

FRIDAY, July 26, 2019 (HealthDay News) — Roxadustat is noninferior to epoetin alfa for increasing hemoglobin levels among patients with anemia who are undergoing dialysis, and is superior to placebo for patients not undergoing dialysis, according to two studies published in the July 24 issue of the New England Journal of Medicine.

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Bariatric Surgery Up in Patients With End-Stage Kidney Disease

THURSDAY, July 25, 2019 (HealthDay News) — For patients with end-stage kidney disease (ESKD), there has been an increase in bariatric surgery, with proportional use of laparoscopic sleeve gastrectomy increasing, according to a study published online July 25 in the Clinical Journal of the American Society of Nephrology.

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Periop Diabetic Ketoacidosis Seen in Patients on SGLT2 Inhibitors

WEDNESDAY, July 24, 2019 (HealthDay News) — Sodium-glucose cotransporter-2 inhibitor (SGLT2i)-associated diabetic ketoacidosis (DKA) may occur after surgery even in patients with normal or near-normal blood glucose levels, according to a review published in the July issue of the British Journal of Anaesthesia.

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CDC: Mortality Rates Continue to Decrease for Hispanic Adults

WEDNESDAY, July 24, 2019 (HealthDay News) — Age-adjusted death rates decreased for Hispanic adults from 2000 through 2017, while for non-Hispanic white and non-Hispanic black adults, the rates have remained stable since 2011-2012, according to a July data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Senate Bill Would Reduce Drug Costs for Seniors

TUESDAY, July 23, 2019 (HealthDay News) — A bill to reduce prescription drug costs for millions of Medicare recipients and lower federal and state health costs has been introduced by two U.S. senators.

AP News Article

Higher eGFR at Dialysis Initiation Tied to Lower Survival in Children

FRIDAY, July 19, 2019 (HealthDay News) — In children with end-stage renal disease (ESRD), a higher estimated glomerular filtration rate (eGFR) at dialysis initiation is associated with lower survival, particularly among children whose initial treatment method is hemodialysis, according to a study published online July 18 in the Journal of the American Society of Nephrology.

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Narrowing Seen in Racial/Ethnic Differences in Home Dialysis Use

THURSDAY, July 18, 2019 (HealthDay News) — Home dialysis use increased from 2005 to 2013, and racial/ethnic differences narrowed over time, according to a study published online July 17 in the Clinical Journal of the American Society of Nephrology.

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About One in 20 Patients Exposed to Preventable Harm

THURSDAY, July 18, 2019 (HealthDay News) — The pooled prevalence of preventable patient harm is 6 percent across a range of medical settings globally, according to a review published online July 17 in The BMJ.

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Rituximab Noninferior to Cyclosporine in Membranous Nephropathy

WEDNESDAY, July 17, 2019 (HealthDay News) — In patients with membranous nephropathy at high risk for progressive disease, rituximab is noninferior to cyclosporine in inducing complete or partial remission of proteinuria at 12 months and is superior in maintaining proteinuria remission up to 24 months, according to a study published in the July 4 issue of the New England Journal of Medicine.

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Non-Vitamin K Oral Anticoagulants May Be Best for Early-Stage CKD

TUESDAY, July 16, 2019 (HealthDay News) — Non-vitamin K oral anticoagulants (NOACs) have a superior benefit-risk profile to that of vitamin K antagonists (VKAs) for patients with early-stage chronic kidney disease (CKD), according to a review published online July 16 in the Annals of Internal Medicine.

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Serious Misdiagnosis-Related Harms Mostly Due to ‘Big Three’

FRIDAY, July 12, 2019 (HealthDay News) — Vascular events, infections, and cancers account for about three-quarters of serious misdiagnosis-related harms, according to a study published online July 11 in Diagnosis.

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Medicare Drug Rebate Plan Withdrawn by Trump Administration

THURSDAY, July 11, 2019 (HealthDay News) — A plan to let Medicare patients receive rebates that drug companies currently pay to insurers and middlemen has been withdrawn by the Trump administration.

AP News Article

Capping Work Hours in Residency Does Not Impact Outcomes Later

THURSDAY, July 11, 2019 (HealthDay News) — Exposure of U.S. physicians to work-hour reforms during residency training is not associated with post-training differences in patient mortality, readmissions, or costs of care, according to a study published online July 11 in The BMJ.

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Uncontrolled Diabetes, Hypertension Rates High in CKD Patients

THURSDAY, July 11, 2019 (HealthDay News) — For patients with chronic kidney disease (CKD), the prevalence of uncontrolled hypertension and diabetes is high and has not improved over time, according to a study published online July 11 in the Clinical Journal of the American Society of Nephrology.

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Health Care Professionals Exhibit Gender Bias

THURSDAY, July 11, 2019 (HealthDay News) — Survey results show that health care professionals have implicit and explicit gender bias, according to a study published online July 5 in JAMA Network Open.

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President to Sign Order to Improve Kidney Disease Care

WEDNESDAY, July 10, 2019 (HealthDay News) — Significant changes in how kidney disease is treated in the United States are outlined in an executive order that was signed Wednesday by President Donald Trump.

AP News Article

Rule Requiring Drug Prices in TV Ads Blocked by Judge

TUESDAY, July 9, 2019 (HealthDay News) — A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge.

The New York Times Article

EHR System-Generated In-Basket Messages Linked to Burnout

TUESDAY, July 9, 2019 (HealthDay News) — Receipt of more than the average number of electronic health record (EHR) system-generated in-basket messages is associated with an increased probability of physician burnout, according to a study published in the July 1 issue of Health Affairs.

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In-Hospital Maternal Mortality Down in Pregnancies With Lupus

TUESDAY, July 9, 2019 (HealthDay News) — In-hospital maternal mortality decreased from 1998 to 2015 in systemic lupus erythematosus (SLE) and non-SLE pregnancies, with a greater decline for SLE pregnancies, according to a study published online July 9 in the Annals of Internal Medicine.

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Considerable Number of Patients Receive Surprise Hospital Charges

TUESDAY, July 2, 2019 (HealthDay News) — Eighteen percent of all emergency department visits and 16 percent of in-network hospital stays have at least one out-of-network charge, according to a report published June 20 by the Kaiser Family Foundation.

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Guidance Issued for Management of Fontan Circulation

TUESDAY, July 2, 2019 (HealthDay News) — A scientific statement with recommendations for follow-up care in patients with Fontan circulation surviving into adulthood was published online July 1 in Circulation.

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