Vaccinations, particularly pneumococcal and influenza vaccines, are indicated for immunocompromised individuals. Vaccination coverage, on the other hand, remains exceedingly low. The purpose of this study was to look at vaccine uptake, knowledge, attitude, and practice (KAP) about certain vaccinations, and the factors that influence willingness to get vaccinated among these individuals. A cross-sectional survey of patients with rheumatic illnesses was done in a tertiary hospital in China. Questionnaires were used to complete baseline evaluations, which included vaccine uptake and KAP toward certain diseases and immunizations. The research was completed by 235 patients. The average age was 39.69 years old, with 66.4 percent of the population being female. Only 6.4 percent of the individuals had received a vaccination in the previous five years. One patient had received influenza immunization, but none had received a pneumococcal vaccine. 3.8 percent got a doctor’s advice to get vaccinated against influenza, pneumococcal disease, or herpes zoster. The most common reasons for not being vaccinated were that it was “unnecessary” and “troublesome to take vaccinations.” Patients would receive influenza or pneumococcal vaccinations if they had heard of them, were aware of the infection, and believed in the vaccine’s safety and dependability. 

In China, vaccine coverage among persons with rheumatic illnesses was poor. Methods for increasing KAP toward diseases and vaccines should be implemented.