The treatment of chronic venous disease and varicose veins might result in significant financial and emotional benefits for the patient. The great saphenous vein has been the focus of treatment for a significant amount of time because of the frequency with which cases of incompetence and reflux may be found involving this vein by conducting a review of the published medical literature that pertains to the use of closure procedures for big varicose veins. Extensive searches of the published literature in the English language were carried out up to and including the month of December 2021. We did an in-depth review of the research that has been published on the subject of the removal of big varicose veins. Endovenous thermal ablation is the most common approach for occluding an incompetent great saphenous vein. This procedure is minimally invasive, carries a low risk of complications, and has a high success rate. Methods that are not thermal, those that are not tumescent, and tumescent methods can also be utilized. A comprehensive understanding of vein anatomy, ultrasound, and the processes for vein closure is required to guarantee safe and effective treatment results.