Premature coronary heart disease (CHD) is defined as the occurrence of acute myocardial infarction, stroke, ischemia, or obstructive coronary artery disease before the age of 45. While several factors may contribute to the situation, recent evidence suggests the association of premature CHD with low socioeconomic status (SES). This study aims to investigate the burden of CHD on young-mid adults with low SES.

This is a computer simulation study based on the Cardiovascular Disease Policy Model of the incidence, prevalence, and mortality due to CHD or stroke among adults in the United States. The study included a total of 31.2 million adults aged 35-64 with low SES. Approximately 16 million (51.3%) of the participants were women. The study also included control participants, including those who were at risk of premature CHD due to traditional factors like smoking, obesity, type-2 diabetes, etc. The primary outcome was premature CHD or stroke incidents or death.

The researchers found that 19% of US adults with low SES are likely to develop CHD by the age of 65 years.

The research concluded that close to a quarter of US adults with low socioeconomic status are at a higher risk of developing premature coronary heart disease.