The goal of this study was to look at reported instances of cervical ectopic pregnancy between 2000 and 2018 and compare management techniques and treatment success rates depending on initial patient characteristics. Peer-reviewed citations published between 2000 and 2018 were found by searching PubMed, EMBASE, and Web of Science. Each individual patient’s -hCG level, crown-rump length, or gestational sac diameter was included in the study. Data on the article, patient characteristics, therapy utilized, and results were gathered. The first success was characterized as the resolution of the cervical ectopic pregnancy using the predetermined treatment strategy. The need for further unexpected treatments as a result of the established treatment plan failing was classified as the first failure. The end result was defined as the resolution of the cervical ectopic pregnancy without the need for hysterectomy. A total of 204 papers from 44 nations were evaluated, totaling 454 instances. The initial -hCG level varied from 9 to 286,500, with a median of 14,773, while the gestational age ranged from 4 to 18 weeks, with a median of 7 4/7 weeks. In terms of early success, dilatation and curettage, dilation and curettage coupled with uterine artery embolization, and uterine artery embolization were more successful than methotrexate alone. More than half of the patients needed repeated procedures, with 41 requiring hysterectomy.

The management of cervical ectopic pregnancies should be guided by patient stability, -hCG level, pregnancy size, and fetal heart activity, although a planned multimodal strategy may help.