Researchers conducted this study to perform a systematic review that evaluates the feasibility and outcomes of endoscopic techniques in the management of different odontogenic cysts. A case series of our experience with these minimally invasive techniques were assembled for insight into these procedures’ technical aspects.

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses was used to identify English-language studies that reported using endoscopic techniques in the management of odontogenic cysts. Several medical literature databases were searched for all occurrences in the title or abstract of the terms “odontogenic” and “endoscopic”. 

A systematic review identified 16 case reports or series that described the use of endoscopic techniques to treat odontogenic cysts, including 45 total patients. Histopathologies encountered were radicular and dentigerous cysts and keratocystic odontogenic tumors (n = 12). There were no reported recurrences or significant complications for a mean follow-up of 29 months. A case series of patients in our institution identified seven patients without repetition for a mean follow-up of 10 months.

The study concluded that endonasal endoscopic treatment of various odontogenic cysts is described in the literature and are associated with effective treatment of these lesions for an average follow-up period of >2 years. These techniques can reduce morbidity related to these lesions’ resection, although comparative studies would better define specific indications.