Patients receiving surgical therapy for benign prostatic hyperplasia (BPH)/lower urinary tract symptoms frequently wish to be free of medication (LUTS). Knowing the rates of medication discontinuation after various types of transurethral prostatectomy can help with patient counselling and analysing the relative efficacy of different methods. This study looked at how many people stopped using BPH/LUTS medicines after having a transurethral prostatectomy. After transurethral resection of the prostate, rates of BPH/LUTS drug usage ranged from 15% to 55%, with cessation rates ranging from 54% to 95% across medicines and follow-up durations. In the case of laser prostatectomy, roughly 18% of patients maintained medicines postoperatively, with cessation rates ranging from 53% to 75%. There was little information available about holmium laser enucleation. Medication cessation rates after transurethral needle ablation or microwave treatment, for comparison, were just 15–28 percent.

There are no recommendations or best practises for the use of medicinal treatment after BPH surgery. Following transurethral prostatectomy, there is a significant increase in the usage of BPH/LUTS medications.