WEDNESDAY, Nov. 6, 2019 (HealthDay News) — Canadian women with HIV have a median age of menopause of 48 years, with lower education and hepatitis C coinfection independently associated with menopause at <45 years, according to a study published online Nov. 6 in Menopause.

Nisha Andany, M.D., M.P.H., from the University of Toronto, and colleagues conducted a cross-sectional analysis of data from 229 women in the Canadian HIV Women’s Sexual and Reproductive Health Cohort Study. The authors examined the age at menopause, prevalence of early menopause (age 40 to 45 years) and premature menopause (<40 years), and risk factors for early menopause.

The researchers found that the median age of menopause was 48 years; 29.7 percent of women experienced menopause before age 45 years: 16.6 and 13.1 percent with early and premature menopause, respectively. In univariate analyses, the investigators found that menopause before age 45 years was more likely with birth in Canada, white ethnicity, less than high school education, smoking, recreational drug use, and hepatitis C coinfection. Less than a high school education and hepatitis C coinfection were independently associated with menopause before age 45 years in multivariable modeling (adjusted odds ratios, 2.45 and 1.90, respectively).

“Occurrence of early menopause among women living with HIV has implications for medical practitioners caring for these women, as it may impact counseling and management,” the authors write.

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