Published case studies have small cohorts and poor, making it difficult to draw firm conclusions on the efficacy of Mohs micrographic surgery (MMS) for sebaceous carcinoma (SC). Because the technique allows for tissue conservation by performing a full peripheral and deep margin assessment before repair, Mohs micrographic surgery is ideally suited for functional and cosmetically delicate areas like the face. In addition, there is a lack of information about how Mohs surgeons and oculoplastic surgeons work together to provide care.

The goals of this study are to evaluate the local recurrence and distant metastasis rates following MMS of facial SC and to describe how Mohs and oculoplastic surgeons work together to provide care.  Cases of facial SC at a single institution treated with MMS between January 2005 and August 2020 were detected retrospectively. Both the tumor’s makeup and its prognosis were documented. Analyses, both descriptive and predictive, were conducted.

There were 49 cases examined, and the average duration of follow-up was 51 months. Periorbital, suborbital, and nasal ala were the most prevalent locations. After MMS, there was no local recurrence in any of the patients. However, a metastatic recurrence was observed in one patient with Muir-Torre syndrome (at 82.9 months). Oculoplastic reconstruction and Mohs micrographic surgery (MMS) were conducted in both stages of treatment for all patients. Tissue-sparing Mohs micrographic surgery (MMS) performed in collaboration with oculoplastic surgeons can minimize SC recurrence and improve facial aesthetics and function in patients with SC of the central face.