There is evidence that there is a link between bullous pemphigoid (BP) and a variety of neurological disorders. It is uncertain if neurological cancer is a risk factor for BP. The study’s goal was to look at the risk of future BP in individuals with neurological tumours. Between 2000 and 2012, data from the Taiwan National Health Insurance Research Database were used to conduct this countrywide population-based cohort research. A total of 8313 patients with neurological cancer and 33,252 age-, gender-, and index-date-matched controls were enrolled in the study. The HR for subsequent BP in patients with neurological cancer was calculated using a Cox model and a Fine-Gray competing risk model, with death as the competing event. Blood pressure incidence rates per 100,000 person-years were 37.2 in patients with neurological malignancy and 6.8 in controls. 5.49 was the crude incidence rate ratio. For patients with neurological malignancy, the meantime to the incidence of BP was 4.48 3.40 years. The incidence of BP was considerably raised by neurological malignancy, age per year, and dementia.
With a relatively small interval of 4.5 years, neurological tumours raised the chance of future BP by 2.4-fold.
Reference: https://link.springer.com/article/10.1007/s40257-019-00494-y
