Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for November 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Fewer Interval Cancers Diagnosed With Supplemental MRI for Dense Breasts

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — For women with extremely dense breast tissue and normal results on mammography, the use of supplemental magnetic resonance imaging (MRI) results in diagnosis of fewer interval cancers than mammography alone during a two-year screening period, according to a study published in the Nov. 28 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Cancer Patients Need More Info on Side Effects of Radiation Tx

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — Although most cancer patients do not experience anticipated potential adverse effects of radiation therapy, more than one-third have adverse effects that they wish they had known more about, according to a study published online Nov. 20 in the Journal of Oncology Practice.

Abstract/Full Text (subscription or payment may be required)

Study Supports PSA Screening for Male BRCA2 Carriers

WEDNESDAY, Nov. 27, 2019 (HealthDay News) — Systematic prostate-specific antigen (PSA) screening is advised for men who are carriers of the BRCA2 mutation, which is associated with a higher incidence of prostate cancer, younger age at diagnosis, and clinically significant tumors, according to the interim results of a study published in the December issue of European Urology.

Abstract/Full Text

U.S. Life Expectancy Dropped Since 2014 for Working-Age Adults

TUESDAY, Nov. 26, 2019 (HealthDay News) — U.S. life expectancy increased from 1959 to 2016 but has been decreasing since 2014, according to research published in the Nov. 26 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Potentially Tainted Marijuana Sold in Colorado

TUESDAY, Nov. 26, 2019 (HealthDay News) — A warning about possibly contaminated and moldy recreational and medical marijuana has been issued by Colorado officials.

CNN Article

Many Cancer Patients Interested in Pathology Consultations

TUESDAY, Nov. 26, 2019 (HealthDay News) — When surveyed, a majority of cancer patients expressed interest in participating in a patient-pathologist consultation program, according to a study recently published in the Archives of Pathology & Laboratory Medicine.

Abstract/Full Text (subscription or payment may be required)

Cancer Patients With Obesity Show Poorer Psychosocial Health

TUESDAY, Nov. 26, 2019 (HealthDay News) — Patients with breast or prostate cancer who are obese score higher in psychosocial problem-related distress than nonobese patients, according to a study recently published in Psycho-Oncology.

Abstract/Full Text (subscription or payment may be required)

Elevated Risk for CVD Mortality Observed in U.S. Cancer Patients

MONDAY, Nov. 25, 2019 (HealthDay News) — Cancer patients have elevated cardiovascular disease (CVD) mortality risk, with the highest risk seen in the first year after cancer diagnosis, according to a study published online Nov. 24 in the European Heart Journal.

Abstract/Full Text
Editorial

Racial Differences Found in Gene Panels for Prostate Cancer Prognosis

MONDAY, Nov. 25, 2019 (HealthDay News) — For three commercial panels for prostate cancer prognosis, gene expression differs for European-American men (EAM) and African-American men (AAM), according to a study published online Nov. 22 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract/Full Text (subscription or payment may be required)

Endocrine Therapy Lowers QOL for Breast Cancer Patients

MONDAY, Nov. 25, 2019 (HealthDay News) — Endocrine therapy reduces the quality of life of breast cancer patients, especially for postmenopausal women, according to a study recently published in the Annals of Oncology.

Abstract/Full Text (subscription or payment may be required)

Electronic Health Record Usability Graded F by Physicians

FRIDAY, Nov. 22, 2019 (HealthDay News) — The usability of current electronic health records (EHRs) is classified as unacceptable, with physician-rated EHR usability independently linked to the odds of burnout, according to a study published online Nov. 14 in the Mayo Clinic Proceedings.

Abstract/Full Text

Testosterone Replacement May Benefit Younger Male Cancer Survivors

FRIDAY, Nov. 22, 2019 (HealthDay News) — Testosterone replacement is associated with an improvement in body composition among younger male cancer survivors with low-normal morning total serum testosterone, according to a study published online Nov. 12 in PLOS Medicine.

Abstract/Full Text

Treatment Beneficial for Nonagenarians With Lung Cancer

FRIDAY, Nov. 22, 2019 (HealthDay News) — Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a study published online Nov. 18 in the Annals of Thoracic Surgery.

Abstract/Full Text (subscription or payment may be required)

Threshold for Breast Cancer Recurrence Score Differs by Sex

THURSDAY, Nov. 21, 2019 (HealthDay News) — The Oncotype DX Breast Recurrence Score (RS) is associated with mortality at a lower threshold for men versus women with breast cancer, according to a study published online Nov. 20 in Clinical Cancer Research.

Abstract/Full Text (subscription or payment may be required)

DCNN Software Aids Detection of Malignant Lung Nodules on CXR

THURSDAY, Nov. 21, 2019 (HealthDay News) — Using deep convolutional neural network (DCNN) software can improve detection of malignant pulmonary nodules on chest radiographs, according to a study published online Nov. 12 in Radiology.

Abstract/Full Text

H. Pylori Infection Must Be Wiped Out to Cut Gastric Cancer Risk

THURSDAY, Nov. 21, 2019 (HealthDay News) — Only complete eradication of Helicobacter pylori infection, not treatment alone, will reduce the risk for developing stomach cancer, according to a study recently published in Gastroenterology.

Abstract/Full Text (subscription or payment may be required)

Radiation From CT Scans Linked to Thyroid Cancer, Leukemia

THURSDAY, Nov. 21, 2019 (HealthDay News) — Exposure to medical radiation from computed tomography (CT) scans is associated with an increased risk for thyroid cancer and leukemia, according to a study published online Nov. 19 in JNCI Cancer Spectrum.

Abstract/Full Text (subscription or payment may be required)

Employee Premiums, Deductibles Eating Larger Share of Income

THURSDAY, Nov. 21, 2019 (HealthDay News) — During the last decade, health care costs have eaten up a larger share of income for millions of middle-class Americans with employer coverage, according to Trends in Employer Health Care Coverage, 2008-2018, a Nov. 21 report from The Commonwealth Fund.

More Information

More Appropriate Prostate Cancer Tx Seen at Multidisciplinary Clinic

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — Receiving care at a multidisciplinary (MultiD) clinic facilitates adherence to evidence-based national treatment guidelines for prostate cancer, according to a study published online Nov. 19 in Cancer.

Abstract/Full Text (subscription or payment may be required)

Cervical Cancer Screening Remains Low in Women Ages 45 to 65 Years

TUESDAY, Nov. 19, 2019 (HealthDay News) — Cervical cancer screening rates are only about 70 percent among women ages 45 to 65 years, according to a study published online Nov. 1 in Preventive Medicine.

Abstract/Full Text (subscription or payment may be required)

Incidence of Squamous Cell Carcinoma of the Anus Increasing

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — There has been an increase in the incidence of squamous cell carcinoma of the anus (SCCA) in the United States, according to a study published online Nov. 19 in the Journal of the National Cancer Institute.

Abstract/Full Text (subscription or payment may be required)

Cancer Yield Similar for Dense Breast Ultrasound After DM, DBT

WEDNESDAY, Nov. 20, 2019 (HealthDay News) — There is no significant difference in breast cancer detection rates with dense breast ultrasound screening following digital mammography (DM) versus digital breast tomosynthesis (DBT), according to a study recently published in the American Journal of Roentgenology.

Abstract/Full Text (subscription or payment may be required)

Cancer Patients Say Ask Before Using Medical Records for Research

TUESDAY, Nov. 19, 2019 (HealthDay News) — Oncology patients would prefer to be asked for their consent before deidentified data from their medical records are used for research, according to a study recently published in the Journal of Clinical Oncology.

Abstract/Full Text (subscription or payment may be required)

Endurance Exercise May Offer Vascular Benefit in Sickle Cell Disease

TUESDAY, Nov. 19, 2019 (HealthDay News) — Endurance exercise training may improve skeletal muscle microvasculature in patients with sickle cell disease (SCD), according to a study published online Nov. 19 in Blood.

Abstract/Full Text (subscription or payment may be required)

CDC: ~20 Percent of U.S. Adults Currently Use Tobacco Products

TUESDAY, Nov. 19, 2019 (HealthDay News) — In 2018, 19.7 percent of U.S. adults reported currently using any tobacco products, according to research published in the Nov. 15 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Bipartisan Bill to Curb Drug Costs Backed by White House

MONDAY, Nov. 18, 2019 (HealthDay News) — A bipartisan Senate bill that would curb prescription drug costs is being backed by the Trump administration as a new poll shows that many Americans think the White House has done little to tackle the issue.

AP News Article

White House Wants Hospitals, Insurers to Provide Actual Costs of Care

MONDAY, Nov. 18, 2019 (HealthDay News) — New rules requiring hospitals and insurers to disclose the actual prices for common tests and procedures before they are performed have been proposed by the Trump Administration.

AP News Article

Studies Confirm Safety of 9-Valent HPV Vaccination

MONDAY, Nov. 18, 2019 (HealthDay News) — The safety of the 9-valent human papillomavirus vaccine (9vHPV) has been confirmed, according to two studies published online Nov. 18 in Pediatrics.

Abstract/Full Text – Shimabukuro (subscription or payment may be required)
Abstract/Full Text – Donahue (subscription or payment may be required)
Editorial (subscription or payment may be required)

Common TB Vaccine Associated With Lower Lung Cancer Rates

MONDAY, Nov. 18, 2019 (HealthDay News) — Childhood vaccination with the bacille Calmette-Guérin (BCG) vaccine is associated with a reduced risk for lung cancer, according to a study published online Sept. 25 in JAMA Network Open.

Abstract/Full Text

Pembrolizumab Prolongs Survival in Advanced Head, Neck Cancer

FRIDAY, Nov. 15, 2019 (HealthDay News) — The checkpoint inhibitor pembrolizumab prolongs survival in patients with certain head and neck cancers, according to a phase 3 study published online Oct. 31 in The Lancet.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Survey of U.S. Registered Nurses Points to Worsening Shortages

THURSDAY, Nov. 14, 2019 (HealthDay News) — The 2019 AMN Healthcare Survey of Registered Nurses raises concerns about the outlook for the nursing profession in the United States.

2019 Survey of Registered Nurses

Minimum Age to Buy Tobacco, E-Cigarettes Raised in NY State

THURSDAY, Nov. 14, 2019 (HealthDay News) — The minimum age to buy tobacco and electronic cigarette products in New York State is now 21.

CNN Article

Four Studies Look at Global Burden of Digestive Diseases

THURSDAY, Nov. 14, 2019 (HealthDay News) — Global burdens of colorectal cancer, pancreatic cancer, inflammatory bowel disease (IBD), and stomach cancer increased from 1990 to 2017, according to four studies published online Oct. 21 in The Lancet Gastroenterology and Hepatology. The studies were published to coincide with the United European Gastroenterology Week, held from Oct. 19 to 23 in Barcelona, Spain.

Abstract/Full Text – Colorectal Cancer
Editorial
Abstract/Full Text – Pancreatic Cancer
Editorial
Abstract/Full Text – IBD
Editorial
Abstract/Full Text – Stomach Cancer
Editorial
More Information

Tobacco Cessation Programs May Up Quit Rates in Cancer Patients

THURSDAY, Nov. 14, 2019 (HealthDay News) — Enrolling actively smoking oncology patients into a comprehensive tobacco cessation program may help patients sustain long-term abstinence from smoking and improve their cancer treatment outcomes, according to a study recently published in JAMA Network Open.

Abstract/Full Text
Editorial

Secondary Surgical Cytoreduction Not Superior in Ovarian Cancer

THURSDAY, Nov. 14, 2019 (HealthDay News) — For patients with platinum-sensitive recurrent ovarian cancer, secondary surgical cytoreduction followed by chemotherapy does not result in longer overall survival than chemotherapy alone, according to a study published in the Nov. 14 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Invasive Melanoma Incidence Decreasing in Teens, Young Adults

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — Melanoma incidence seems to be decreasing in adolescents and young adults, according to a study published online Nov. 13 in JAMA Dermatology.

Abstract/Full Text (subscription or payment may be required)

Physical Activity After Cancer Diagnosis Improves Survival

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — At least 150 minutes per week of moderate-intensity physical activity is associated with lower all-cause mortality among postmenopausal breast cancer patients, regardless of their levels of physical activity before diagnosis, according to a study published online Nov. 7 in Breast Cancer Research.

Abstract/Full Text

U.S. States Can Do More to Prevent, Treat Lung Cancer

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — States can do more to prevent and treat lung cancer, according to a report published online Nov. 13 by the American Lung Association.

Press Release
State of Lung Cancer 2019

Imaging Rates Continue to Rise Despite Efforts to Reduce

WEDNESDAY, Nov. 13, 2019 (HealthDay News) — Despite initiatives to reduce the use of medical imaging, rates continue to rise in both the United States and Ontario, Canada, according to a study recently published in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Testosterone Therapy Tied to Increase in Short-Term VTE Risk

TUESDAY, Nov. 12, 2019 (HealthDay News) — For men with and without hypogonadism, testosterone therapy is associated with an increased short-term risk for venous thromboembolism (VTE), according to a study published online Nov. 11 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Test of Vascular Function May Predict Solid-Tumor Cancer Risk

THURSDAY, Nov. 7, 2019 (HealthDay News) — Microvascular endothelial dysfunction is associated with an increased risk for solid-tumor cancer, according to a study published online Oct. 31 in the European Journal of Preventive Cardiology.

Abstract/Full Text

Lung Cancer Incidence Rates Generally Declined From 2007 to 2016

FRIDAY, Nov. 8, 2019 (HealthDay News) — The incidence rates of lung cancer declined in most age and sex groups from 2007 to 2016, with the smallest decrease seen among women living in nonmetropolitan counties, according to research published in the Nov. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Hematology Experiences Linked to Hematology-Only Career Plan

FRIDAY, Nov. 8, 2019 (HealthDay News) — Exposure to clinical training and mentorship experiences in hematology throughout training is associated with fellows’ plans to enter hematology-only careers, according to a study published online Oct. 31 in Blood Advances.

Abstract/Full Text

Juul Stops Sales of Mint-Flavored E-Cigarettes

FRIDAY, Nov. 8, 2019 (HealthDay News) — Juul Labs will halt sales of its mint-flavored electronic cigarettes, the company announced Thursday.

AP News Article

Patients With Cirrhosis Have Considerable Financial Burden

FRIDAY, Nov. 8, 2019 (HealthDay News) — The considerable financial burden of cirrhosis medical care is associated with lower surveillance for hepatocellular carcinoma (HCC), according to a study presented at The Liver Meeting, the annual meeting of the American Association for the Study of Liver Diseases, held from Nov. 8 to 12 in Boston.

Press Release
More Information

Number of Potentially Excess Deaths Up in Nonmetropolitan Counties

THURSDAY, Nov. 7, 2019 (HealthDay News) — During 2010 to 2017, nonmetropolitan counties had higher percentages of potentially excess deaths from five leading causes than metropolitan counties nationwide, according to research published in the Nov. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Lenalidomide Delays Progression in Smoldering Multiple Myeloma

THURSDAY, Nov. 7, 2019 (HealthDay News) — Lenalidomide significantly delays progression to symptomatic multiple myeloma in patients with smoldering multiple myeloma, according to a study published online Oct. 25 in the Journal of Clinical Oncology.

Abstract/Full Text

PSA Levels No Different With Exposure to Antidiabetes Meds

THURSDAY, Nov. 7, 2019 (HealthDay News) — Men exposed to antidiabetic medications do not have different prostate-specific antigen (PSA) levels, and prostate cancer detection rates at biopsy do not differ regardless of trigger PSA levels, according to a study published online Nov. 6 in JAMA Network Open.

Abstract/Full Text
Editorial

Mailing HPV Kits to Underscreened Women Can Up Screening

WEDNESDAY, Nov. 6, 2019 (HealthDay News) — Mailing human papillomavirus (HPV) kits to underscreened women is associated with increased screening uptake but does not significantly increase precancer detection or treatment, according to a study published online Nov. 6 in JAMA Network Open.

Abstract/Full Text
Editorial

Exercise Should Be Prescribed to Cancer Survivors

WEDNESDAY, Nov. 6, 2019 (HealthDay News) — Exercise should be prescribed for cancer survivors, according to recommendations published in the November issue of Medicine & Science in Sports & Exercise and an article published online Oct. 16 in CA: A Cancer Journal for Clinicians.

Exercise Guidelines for Cancer Survivors
Abstract/Full Text – Schmitz Article

Cardiorespiratory Fitness May Improve Lung Cancer Outcomes

WEDNESDAY, Nov. 6, 2019 (HealthDay News) — Higher cardiorespiratory fitness is associated with a lower risk for lung cancer incidence in former smokers and a reduced risk for cancer mortality in current smokers diagnosed with lung cancer, according to a study published in the November issue of the American Journal of Preventive Medicine.

Abstract/Full Text

Medical Practices Burdened by Regulatory Requirements

TUESDAY, Nov. 5, 2019 (HealthDay News) — The vast majority of group medical practices report that regulatory requirements, including prior authorization and quality payment programs, are burdensome, according to a survey released by the Medical Group Management Association.

Annual Regulatory Burden Survey

Number of Cancer Patients Using Gabapentinoids Up Since 2005

TUESDAY, Nov. 5, 2019 (HealthDay News) — Between 2005 and 2015, there was a more than twofold increase in the percentage of adults with cancer using gabapentinoids, according to a study published online Oct. 25 in Supportive Care in Cancer.

Abstract/Full Text (subscription or payment may be required)

Running Participation Linked to Reduced Risk for Mortality

TUESDAY, Nov. 5, 2019 (HealthDay News) — Running participation is associated with a significantly lower risk for all-cause, cardiovascular, and cancer mortality, according to a review and meta-analysis published online Nov. 4 in the British Journal of Sports Medicine.

Abstract/Full Text

Fecal Microbiota Transplant Cuts Bloodstream Infection in C. diff

TUESDAY, Nov. 5, 2019 (HealthDay News) — Patients with recurrent Clostridioides difficile infection (CDI) who receive treatment with fecal microbiota transplantation (FMT) are less likely to develop a primary bloodstream infection (BSI) than those receiving antibiotics, according to a study published online Nov. 5 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Dietary Patterns May Possibly Be Linked to Prostate Cancer Risk

TUESDAY, Nov. 5, 2019 (HealthDay News) — Plant-based diets are associated with a decreased or unchanged risk for prostate cancer, while animal-based diets, especially those containing dairy products, are associated with an increased or unchanged risk, according to a review published in the November issue of the Journal of the American Osteopathic Association.

Abstract/Full Text

CRC Screening Recommended for Average-Risk Adults Age 50 to 75

MONDAY, Nov. 4, 2019 (HealthDay News) — Average-risk adults between the ages of 50 and 75 years should be screened for colorectal cancer, with the screening test selected based on discussion with patients, according to a guidance statement from the American College of Physicians published online Nov. 5 in the Annals of Internal Medicine.

Abstract/Full Text
Editorial (subscription or payment may be required)

Seriously Ill Medicare Beneficiaries Face Financial Hardship

MONDAY, Nov. 4, 2019 (HealthDay News) — Seriously ill Medicare enrollees experience considerable financial distress, according to a report published in the November issue of Health Affairs.

Abstract/Full Text (subscription or payment may be required)

Dr. Stephen Hahn Nominated to Head FDA

MONDAY, Nov. 4, 2019 (HealthDay News) — Radiation oncology expert Stephen Hahn, M.D., has been nominated as the new U.S. Food and Drug Administration commissioner.

CNN Article

Recommendations Developed to Address Clinician Burnout

FRIDAY, Nov. 1, 2019 (HealthDay News) — In Taking Action Against Clinician Burnout, a new report published online Oct. 23 by the National Academies of Sciences, Engineering, and Medicine, recommendations are presented to address clinician burnout.

Taking Action Against Clinician Burnout

U.S. Oncologist Shortage May Impact Women’s Health

FRIDAY, Nov. 1, 2019 (HealthDay News) — Anticipated future shortages of oncology providers may have a serious and specific impact on women’s health care, according to Doximity’s 2019 Women’s Health and Oncologist Workforce Analysis.

More Information

Risk for Second Primary Malignancy Up in CLL Survivors

FRIDAY, Nov. 1, 2019 (HealthDay News) — Survivors of chronic lymphocytic leukemia (CLL) have an increased risk for second primary malignancy (SPM), according to a study published online Sept. 30 in Blood Cancer Journal.

Abstract/Full Text

Many Oncologists Fail to Discuss Costs of Genomic Testing

FRIDAY, Nov. 1, 2019 (HealthDay News) — Only half of oncologists who discuss genomic testing with patients report that they often discuss the likely costs of testing and related treatments, according to a study published online Nov. 1 in the Journal of the National Cancer Institute.

Abstract/Full Text (subscription or payment may be required)

Many Not Receiving Guideline-Concordant Tx for Lung Cancer

FRIDAY, Nov. 1, 2019 (HealthDay News) — Many lung cancer patients in the United States receive no treatment or less intensive treatment than recommended, according to a study published online Nov. 1 in the Annals of the American Thoracic Society.

Abstract/Full Text (subscription or payment may be required)

Copyright © 2019 ScoutNews, LLC. All rights reserved.
healthday