The oral food challenge (OFC) is a particular and important method used in clinical practise to determine a person’s level of tolerance for different meals when identifying food-related allergies. The procedures used by OFC vary per country. The purpose of this review is to assess various target dosages and to identify the time interval between doses utilised for OFC. Researchers looked at recent studies on target doses and time between doses and discovered that several journals claimed low target doses and shorter time between doses. A low-dose OFC appears to be a good technique; a time gap of 15 minutes between doses is short, but at least 1 hour is recommended.

Low-dose OFCs appear to be well tolerated and helpful in avoiding full removal of allergy-causing foods. The time gap between doses should be greater than 30 minutes for the OFC technique to be safe.