In this study We explored a huge episode of Haff illness that happened along the Yangtze River in Anhui Province, China, in 2016. Of the 672 cases distinguished during the episode, 83.3% (560/672) happened in Wuhu and Ma’anshan. Patients experienced myalgia (100%) and muscle shortcoming (54.7%). The mean estimation of myoglobin was 330 + 121.2 ng/mL and of serum creatine kinase 5,439.2 + 4,765.1 U/L. Eating crawfish was the solitary basic openness among all cases; 96.8% (240/248) of embroiled crawfish were gotten on the shores of the Yangtze River or its associated ditches. Mean brooding period was 6.2 + 3.8 hours. This case–control study showed that eating the liver of crawfish and eating a huge amount of crawfish were related with an expanded danger for Haff infection. The occasional expansions in crawfish populace along the Yangtze River may clarify the occasional episodes of Haff infection.

Haff infection is an unexplained rhabdomyolysis that happens inside 24 hours after utilization of specific kinds of freshwater or saltwater fish. Therefore we conclude that ensuing flare-ups were distinguished in a few different nations, like Sweden , the previous Soviet Union , Brazil , Japan , and China, the etiology has not yet been resolved. An unidentified warmth stable poison like cyanotoxins or palytoxin, yet principally myotoxic and not neurotoxic, is believed to be the reason for Haff illness; nonetheless, proof supporting this theory has been inadequate

Reference link- https://wwwnc.cdc.gov/eid/article/26/12/19-1186_article

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