FRIDAY, April 17, 2020 (HealthDay News) — Women with lower ovarian reserve do not experience differences in adiposity and glucose metabolism during their reproductive life span compared with women with high ovarian reserve, according to a study published online April 13 in Menopause.

Mina Amiri, Ph.D., from Shahid Beheshti University in Tehran, Iran, and colleagues used data from the Tehran Lipid and Glucose Study to identify 1,015 women (aged 20 to 50 years). Trends of adiposity and glucose metabolism parameters were compared in women with low ovarian reserve status (based on their anti-Mullerian hormone [AMH] levels) versus those with high ovarian reserve during a median follow-up of 16 years.

The researchers found that women in the first and fourth quartiles of age-specific AMH experienced significant positive trends in their adiposity indices, including central obesity, waist-to-hip ratio, waist-to-height ratio, and a body shape index. There was also a negative trend in visceral adiposity index. However, there were no significant differences noted in these parameters between the two groups. Compared with the fourth quartile, women in the first quartile of age-specific AMH were not significantly different for the odds of diabetes and prediabetes.

“In a general population of reproductive-age, apparently healthy females, AMH is not associated with changes in the over-time trend of adiposity and glucose metabolism parameters,” the authors write.

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