In a cohort study involving 244,125 children born in Kaiser Permanente Northern California between 2009 and 2016 who received MCV between the ages of 1 and 2 years, researchers investigated whether parental clinical conditions were associated with fever after a first dose of measles-containing vaccine (MCV) in the child. When feasible, each kid was linked with his or her mother and father. Parental clinical conditions that existed before and after the birth of their kid were discovered. Fever in children was defined as clinic and emergency department visits with a fever code 7–10 days following the first dose of MCV. Using multivariate logistic regression analysis, they looked at the clinical circumstances of parents who had MCV-related fever. Maternal fever, fever following MCV, respiratory infections, migraine, syncope, and essential thrombocythemia were substantially related with MCV-associated fever despite controlling for numerous variables such as healthcare usage. 

MCV-related fever was strongly linked with paternal respiratory illnesses, fever associated with respiratory infections, and vitiligo. Fever in their kid 7–10 days after MCV is related with parental clinical problems, especially fever alone and fever coupled with respiratory illness.

Reference: https://www.tandfonline.com/doi/full/10.1080/21645515.2019.1675458

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