The study’s goal was to examine the zinc status of neonates receiving parenteral nourishment with or without a small intestinal stoma, to estimate the occurrence of zinc shortage, and to identify clinical variables related to plasma zinc levels. All liveborn infants receiving zinc parenteral intake of 500 g kg1 day1 and benefiting from at least one plasma zinc evaluation during hospitalization were included in this monocentric cohort research. In 50 infants split into three groups, 68 zinc doses were administered. 37 of the 50 babies were delivered prematurely. The mean standard deviation plasma zinc level was 14.9 4.3 mol/L, which was comparable across all three groups. Sixty-four percent, 3%, and 34% of zinc levels were within, below, and above normal ranges, respectively. Only one plasma zinc value was lower than the standard range in babies having a jejunostomy. Stoma production was inversely linked to plasma zinc levels. In contrast to patients with minimal intestinal losses, there was no relationship between zinc levels and postmenstrual age in infants with a jejunostomy, indicating that 500 g kg1 day1 was appropriate not only in preterm infants but also in term infants with a jejunostomy.
Plasma zinc levels in neonates with small intestinal stomas drop considerably as stoma output volume increases. Zinc deficiency was avoided in infants with a small bowel stoma who received 500 g kg1 day1 of parenteral zinc.
Reference:https://journals.lww.com/jpgn/Fulltext/2020/04000/Parenteral_Zinc_Intake_in_Newborns_With.28.aspx
