A Respiratory support device is known as a Heated humidified high-flow nasal cannula, originally used in pediatrics for infants with bronchiolitis. No large-scale investigation has determined the current frequency or demographic distribution of Heated humidified high-flow nasal cannula (HFNC) use in children. The main objective of researchers to carry out this study was to determine the frequency and correlates of HFNC use in children presenting to the hospital for asthma, bronchiolitis, or pneumonia. This long-term empirical study was based on electronic health record data from a large regional health information exchange, the Indiana Network for Patient Care (INPC). Age groups between 0-18 years were subjects with recorded hospital encounters at an INPC hospital between 2010–2019 with International Classification of Diseases codes for bronchiolitis, asthma, or pneumonia. Generalized additive models were used for estimating the annual proportions of HNFC use among all hospital encounters. Log-binomial regression models were used to recognize correlates of incident HFNC use and decide the risk ratios of specific subjects receiving HFNC. Unique subjects, around 242,381 with 412,712 hospital encounters, were included in the study between 2010–2019. The 10-y period ubiquity of HFNC use was 2.54% (6,155/242,381), involving 7,974 encounters. Hospital encounters increased by 400%, from 326 in 2010 to 1,310 in 2019, due to the usage of HNFC. This rise was uniformly distributed across all 3 diagnostic categories (bronchiolitis, asthma, and pneumonia). The risk of HFNC usage was remarkably influenced by sex, race, age, and ethnicity. The percentage of all hospital encounters using HFNC increased from 1.11% in 2010 to 3.15% in 2018 during and throughout a period of time. Subjects with multiple diagnoses had a markedly higher risk of receiving HFNC. Over the past decade, the use of HFNC in children presenting to the hospital with the common respiratory disease has increased considerably and is no longer restricted to treating infants with bronchiolitis. Demographic and diagnostic factors significantly altered the frequency of HFNC use.